Rapid de novo evolution of lysis genes in single-stranded RNA phages

Leviviruses are phages with ssRNA genomes that encode a protein (Sgl) that induces host autolysis by interfering with bacterial cell wall synthesis. Identification of sgl genes is complicated by their small size and lack of sequence similarity. Here, Chamakura et al. use bioinformatic and experiment...

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Autores principales:	Karthik R. Chamakura, Jennifer S. Tran, Chandler O’Leary, Hannah G. Lisciandro, Sophia F. Antillon, Kameron D. Garza, Elizabeth Tran, Lorna Min, Ry Young
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/569f574a725c4637a34e4ba1e5b3b9d0
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spelling	oai:doaj.org-article:569f574a725c4637a34e4ba1e5b3b9d02021-12-02T16:49:29ZRapid de novo evolution of lysis genes in single-stranded RNA phages10.1038/s41467-020-19860-02041-1723https://doaj.org/article/569f574a725c4637a34e4ba1e5b3b9d02020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19860-0https://doaj.org/toc/2041-1723Leviviruses are phages with ssRNA genomes that encode a protein (Sgl) that induces host autolysis by interfering with bacterial cell wall synthesis. Identification of sgl genes is complicated by their small size and lack of sequence similarity. Here, Chamakura et al. use bioinformatic and experimental approaches to identify sgl genes in 244 leviviral genomes.Karthik R. ChamakuraJennifer S. TranChandler O’LearyHannah G. LisciandroSophia F. AntillonKameron D. GarzaElizabeth TranLorna MinRy YoungNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karthik R. Chamakura Jennifer S. Tran Chandler O’Leary Hannah G. Lisciandro Sophia F. Antillon Kameron D. Garza Elizabeth Tran Lorna Min Ry Young Rapid de novo evolution of lysis genes in single-stranded RNA phages
description	Leviviruses are phages with ssRNA genomes that encode a protein (Sgl) that induces host autolysis by interfering with bacterial cell wall synthesis. Identification of sgl genes is complicated by their small size and lack of sequence similarity. Here, Chamakura et al. use bioinformatic and experimental approaches to identify sgl genes in 244 leviviral genomes.
format	article
author	Karthik R. Chamakura Jennifer S. Tran Chandler O’Leary Hannah G. Lisciandro Sophia F. Antillon Kameron D. Garza Elizabeth Tran Lorna Min Ry Young
author_facet	Karthik R. Chamakura Jennifer S. Tran Chandler O’Leary Hannah G. Lisciandro Sophia F. Antillon Kameron D. Garza Elizabeth Tran Lorna Min Ry Young
author_sort	Karthik R. Chamakura
title	Rapid de novo evolution of lysis genes in single-stranded RNA phages
title_short	Rapid de novo evolution of lysis genes in single-stranded RNA phages
title_full	Rapid de novo evolution of lysis genes in single-stranded RNA phages
title_fullStr	Rapid de novo evolution of lysis genes in single-stranded RNA phages
title_full_unstemmed	Rapid de novo evolution of lysis genes in single-stranded RNA phages
title_sort	rapid de novo evolution of lysis genes in single-stranded rna phages
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/569f574a725c4637a34e4ba1e5b3b9d0
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Rapid de novo evolution of lysis genes in single-stranded RNA phages

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