The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea

Introduction: Rosacea is manifested by erythema and telangiectasias limited to the regions of cheeks, nose, chin and forehead. Data from the literature indicate a possible causal relationship between Helicobacter pylori infection in the gastrointestinal tract and rosacea, which is confirmed by the i...

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Autores principales:	Ninković-Baroš Đuka, Gajanin Vesna, Kutlija Nevena, Sladojević Igor, Krivokuća Svetozar
Formato:	article
Lenguaje:	EN SR
Publicado:	Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine 2021
Materias:	rosacea clinical course helicobacter pylori, effect of medications Medicine R
Acceso en línea:	https://doaj.org/article/56a1cfd38ecf4a7689adb08fd46bf846
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spelling	oai:doaj.org-article:56a1cfd38ecf4a7689adb08fd46bf8462021-12-05T21:31:53ZThe effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea2490-33292303-795410.5937/scriptamed52-29679https://doaj.org/article/56a1cfd38ecf4a7689adb08fd46bf8462021-01-01T00:00:00Zhttps://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2021/2490-33292103199N.pdfhttps://doaj.org/toc/2490-3329https://doaj.org/toc/2303-7954Introduction: Rosacea is manifested by erythema and telangiectasias limited to the regions of cheeks, nose, chin and forehead. Data from the literature indicate a possible causal relationship between Helicobacter pylori infection in the gastrointestinal tract and rosacea, which is confirmed by the improvement of symptoms and clinical picture of rosacea after administered Helicobacter pylori eradication therapy. The aim of the paper was to determine the frequency of Helicobacter pylori infection in patients with rosacea and to examine the effect of the therapy for eradication of infection of this microorganism on the clinical course of rosacea. Methods: Sixty patients with a diagnosis of rosacea who were treated in 2018 at the Clinic for Skin and Venereal Diseases of the University Clinical Centre of Republic of Srpska were analysed. Patients were examined during their visit to a dermatologist (first week) and after applied therapy (sixth week). Subjects were divided into two groups-group I consisted of subjects in which, in addition to rosacea, the presence of Helicobacter pylori was registered and for whom the topical therapy and triple therapy for eradication of Helicobacter pylori were administered, and group II, which included subjects in which, in addition to rosacea, the presence of Helicobacter pylori was not registered and for whom only topical therapy was administered. Statistical processing was performed in the IBM SPSS Statistics 21 software package. Results: Helicobacter pylori infection was registered in 45 % of patients. Statistical significance was determined between the presence of Helicobacter pylori infection and the presence of pustules in patients with rosacea (p = 0.027), with an occurrence of pustules significantly more frequent in patients belonging to group I (55.6 %) than in patients belonging to group II (24.2 %). Conclusion: Therapy for eradicating Helicobacter pylori infection improves the clinical course of rosacea, especially in the stage of papules and pustules.Ninković-Baroš ĐukaGajanin VesnaKutlija NevenaSladojević IgorKrivokuća SvetozarMedical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicinearticlerosaceaclinical coursehelicobacter pylori, effect of medicationsMedicineRENSRScripta Medica, Vol 52, Iss 3, Pp 199-204 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	rosacea clinical course helicobacter pylori, effect of medications Medicine R
spellingShingle	rosacea clinical course helicobacter pylori, effect of medications Medicine R Ninković-Baroš Đuka Gajanin Vesna Kutlija Nevena Sladojević Igor Krivokuća Svetozar The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea
description	Introduction: Rosacea is manifested by erythema and telangiectasias limited to the regions of cheeks, nose, chin and forehead. Data from the literature indicate a possible causal relationship between Helicobacter pylori infection in the gastrointestinal tract and rosacea, which is confirmed by the improvement of symptoms and clinical picture of rosacea after administered Helicobacter pylori eradication therapy. The aim of the paper was to determine the frequency of Helicobacter pylori infection in patients with rosacea and to examine the effect of the therapy for eradication of infection of this microorganism on the clinical course of rosacea. Methods: Sixty patients with a diagnosis of rosacea who were treated in 2018 at the Clinic for Skin and Venereal Diseases of the University Clinical Centre of Republic of Srpska were analysed. Patients were examined during their visit to a dermatologist (first week) and after applied therapy (sixth week). Subjects were divided into two groups-group I consisted of subjects in which, in addition to rosacea, the presence of Helicobacter pylori was registered and for whom the topical therapy and triple therapy for eradication of Helicobacter pylori were administered, and group II, which included subjects in which, in addition to rosacea, the presence of Helicobacter pylori was not registered and for whom only topical therapy was administered. Statistical processing was performed in the IBM SPSS Statistics 21 software package. Results: Helicobacter pylori infection was registered in 45 % of patients. Statistical significance was determined between the presence of Helicobacter pylori infection and the presence of pustules in patients with rosacea (p = 0.027), with an occurrence of pustules significantly more frequent in patients belonging to group I (55.6 %) than in patients belonging to group II (24.2 %). Conclusion: Therapy for eradicating Helicobacter pylori infection improves the clinical course of rosacea, especially in the stage of papules and pustules.
format	article
author	Ninković-Baroš Đuka Gajanin Vesna Kutlija Nevena Sladojević Igor Krivokuća Svetozar
author_facet	Ninković-Baroš Đuka Gajanin Vesna Kutlija Nevena Sladojević Igor Krivokuća Svetozar
author_sort	Ninković-Baroš Đuka
title	The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea
title_short	The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea
title_full	The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea
title_fullStr	The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea
title_full_unstemmed	The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea
title_sort	effect of presence of helicobacter pylori on the severity and clinical course of rosacea
publisher	Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine
publishDate	2021
url	https://doaj.org/article/56a1cfd38ecf4a7689adb08fd46bf846
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The effect of presence of Helicobacter pylori on the severity and clinical course of Rosacea

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