Puma and Trail/Dr5 pathways control radiation-induced apoptosis in distinct populations of testicular progenitors.

Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after gamma-irradiation but the death effectors are still poorly characterized. Our data demonstrate that both intrinsic and extrinsic apoptotic pathways are involved, and especia...

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Autores principales: Mathieu Coureuil, Nicolas Ugolin, Marie Tavernier, Sylvie Chevillard, Vilma Barroca, Pierre Fouchet, Isabelle Allemand
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/56a6a1157cbd42bd8ae9ba37f0e9a5e5
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