Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners

Abstract We evaluated the feasibility and image quality of prospective electrocardiography (ECG)-triggered coronary computed tomography angiography (CCTA) using a body surface area (BSA) protocol for contrast-medium (CM) administration on both second- and third-generation scanners (Flash and Force C...

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Autores principales:	Liang Jin, Yiyi Gao, Yingli Sun, Cheng Li, Pan Gao, Wei Zhao, Ming Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/56af109754fe410fa95e141afbb715e6
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spelling	oai:doaj.org-article:56af109754fe410fa95e141afbb715e62021-12-02T18:37:07ZContrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners10.1038/s41598-020-73915-22045-2322https://doaj.org/article/56af109754fe410fa95e141afbb715e62020-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-73915-2https://doaj.org/toc/2045-2322Abstract We evaluated the feasibility and image quality of prospective electrocardiography (ECG)-triggered coronary computed tomography angiography (CCTA) using a body surface area (BSA) protocol for contrast-medium (CM) administration on both second- and third-generation scanners (Flash and Force CT), without using heart rate control. One-hundred-and-eighty patients with suspected coronary heart disease undergoing CCTA were divided into groups A (BSA protocol for CM on Flash CT), B (body mass index (BMI)-matched patients; BMI protocol for CM on Flash CT), and C (BMI-matched patients; BSA protocol for CM on Force CT). Patient characteristics, quantitative and qualitative measures, and radiation dose were compared between groups A and B, and A and C. Of the 180 patients, 99 were male (median age, 62 years). Average BSA in groups A, B, and C was 1.80 ± 0.17 m2, 1.74 ± 0.16 m2, and 1.64 ± 0.17 m2, respectively, with groups A and C differing significantly (P < 0.001). Contrast volume (50.50 ± 8.57 mL vs. 45.00 ± 6.18 mL) and injection rate (3.90 ± 0.44 mL/s vs. 3.63 ± 0.22 mL/s) differed significantly between groups A and C (P < 0.001). Groups A and C (both: all CT values > 250 HU, average scores > 4) achieved slightly lower diagnostic image quality than group B. The BSA protocol for CM administration was feasible in both Flash and Force CT, and therefore may be valuable in clinical practice.Liang JinYiyi GaoYingli SunCheng LiPan GaoWei ZhaoMing LiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Liang Jin Yiyi Gao Yingli Sun Cheng Li Pan Gao Wei Zhao Ming Li Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
description	Abstract We evaluated the feasibility and image quality of prospective electrocardiography (ECG)-triggered coronary computed tomography angiography (CCTA) using a body surface area (BSA) protocol for contrast-medium (CM) administration on both second- and third-generation scanners (Flash and Force CT), without using heart rate control. One-hundred-and-eighty patients with suspected coronary heart disease undergoing CCTA were divided into groups A (BSA protocol for CM on Flash CT), B (body mass index (BMI)-matched patients; BMI protocol for CM on Flash CT), and C (BMI-matched patients; BSA protocol for CM on Force CT). Patient characteristics, quantitative and qualitative measures, and radiation dose were compared between groups A and B, and A and C. Of the 180 patients, 99 were male (median age, 62 years). Average BSA in groups A, B, and C was 1.80 ± 0.17 m2, 1.74 ± 0.16 m2, and 1.64 ± 0.17 m2, respectively, with groups A and C differing significantly (P < 0.001). Contrast volume (50.50 ± 8.57 mL vs. 45.00 ± 6.18 mL) and injection rate (3.90 ± 0.44 mL/s vs. 3.63 ± 0.22 mL/s) differed significantly between groups A and C (P < 0.001). Groups A and C (both: all CT values > 250 HU, average scores > 4) achieved slightly lower diagnostic image quality than group B. The BSA protocol for CM administration was feasible in both Flash and Force CT, and therefore may be valuable in clinical practice.
format	article
author	Liang Jin Yiyi Gao Yingli Sun Cheng Li Pan Gao Wei Zhao Ming Li
author_facet	Liang Jin Yiyi Gao Yingli Sun Cheng Li Pan Gao Wei Zhao Ming Li
author_sort	Liang Jin
title	Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
title_short	Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
title_full	Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
title_fullStr	Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
title_full_unstemmed	Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
title_sort	contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/56af109754fe410fa95e141afbb715e6
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Contrast medium administration with a body surface area protocol in step-and-shoot coronary computed tomography angiography with dual-source scanners

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