Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
Mitochondrial fission and fusion are important mechanisms to maintain mitochondrial function. Here, the authors report that middle-aged flies have more elongated, or ‘hyper-fused’ mitochondria, and show that induction of mitochondrial fission in midlife, but not in early life, extends the health and...
Guardado en:
Autores principales: | Anil Rana, Matheus P. Oliveira, Andy V. Khamoui, Ricardo Aparicio, Michael Rera, Harry B. Rossiter, David W. Walker |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/56b69cd7b02648e89c37e7fc3efa2845 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
DRP3 and ELM1 are required for mitochondrial fission in the liverwort Marchantia polymorpha
por: Nagisa Nagaoka, et al.
Publicado: (2017) -
Social perception of young adults prolongs the lifespan of aged Drosophila
por: Li-Chun Cho, et al.
Publicado: (2021) -
Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
por: Javier Prieto, et al.
Publicado: (2016) -
Baicalein suppresses lipopolysaccharide-induced acute lung injury by regulating Drp1-dependent mitochondrial fission of macrophages
por: Cheng Jiang, et al.
Publicado: (2022) -
Gold nanoparticles enhance TRAIL sensitivity through Drp1-mediated apoptotic and autophagic mitochondrial fission in NSCLC cells
por: Ke S, et al.
Publicado: (2017)