VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation

Protein homeostasis is crucial for maintaining a variety of cellular functions. Here the authors show that valosin-containing protein and its cofactors regulate tubular ER formation and protein synthesis efficiency, thereby control dendritic spine formation in neurons.

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Auteurs principaux: Yu-Tzu Shih, Yi-Ping Hsueh
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/56b9ffe539cc4faf8078eb7f130ffa07
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