Validation of Pretreatment Methods for the In-Process Quantification of Foot-and-Mouth Disease Vaccine Antigens

Validation of Pretreatment Methods for the In-Process Quantification of Foot-and-Mouth Disease Vaccine Antigens

Foot-and-mouth disease (FMD), caused by the FMD virus (FMDV), is controlled by vaccine policy in many countries. For vaccine potency, the content of intact virus particles (146S antigens) is critical, and the sucrose density gradient (SDG) fractionation is the gold standard for the quantification of...

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Autores principales: Ah-Young Kim, Sun Young Park, Sang Hyun Park, Jong Sook Jin, Eun-Sol Kim, Jae Young Kim, Jong-Hyeon Park, Young-Joon Ko
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
foot-and-mouth disease (FMD)
pretreatment
quantification
vaccine antigen
SE-HPLC
Medicine
R
Acceso en línea:https://doaj.org/article/56bdcd52039a4b2ea7bd5dcf122b54f5
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