Macrophage depletion by free bisphosphonates and zoledronate-loaded red blood cells.
Bisphosphonates, besides being important drugs for the treatment of various bone diseases, could also be used to induce apoptosis in macrophage-like and cancer cells. However, their activity in vivo is limited by a short plasma half-life and rapid uptake within bone. Therefore, several delivery syst...
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Autores principales: | Raffaella Sabatino, Antonella Antonelli, Serafina Battistelli, Reto Schwendener, Mauro Magnani, Luigia Rossi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/56be3593f83b4891b7e1e408295e6da1 |
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