Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage

Echovirus 30 (E30) belongs to the Enterovirus-B group and causes aseptic meningitis in humans. Here, the authors present the cryo-EM structures of the E30 E-particle, A-particle and the mature virion, as well as structures of E30 in complex with its receptor FcRn and CD55, and furthermore they descr...

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Autores principales:	Kang Wang, Ling Zhu, Yao Sun, Minhao Li, Xin Zhao, Lunbiao Cui, Li Zhang, George F. Gao, Weiwei Zhai, Fengcai Zhu, Zihe Rao, Xiangxi Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/56c313c3a4bd4f1b8aea3e2cd8500956
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spelling	oai:doaj.org-article:56c313c3a4bd4f1b8aea3e2cd85009562021-12-02T19:10:37ZStructures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage10.1038/s41467-020-18251-92041-1723https://doaj.org/article/56c313c3a4bd4f1b8aea3e2cd85009562020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18251-9https://doaj.org/toc/2041-1723Echovirus 30 (E30) belongs to the Enterovirus-B group and causes aseptic meningitis in humans. Here, the authors present the cryo-EM structures of the E30 E-particle, A-particle and the mature virion, as well as structures of E30 in complex with its receptor FcRn and CD55, and furthermore they describe a structure-based algorithm that allows the prediction of EV receptor usage.Kang WangLing ZhuYao SunMinhao LiXin ZhaoLunbiao CuiLi ZhangGeorge F. GaoWeiwei ZhaiFengcai ZhuZihe RaoXiangxi WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kang Wang Ling Zhu Yao Sun Minhao Li Xin Zhao Lunbiao Cui Li Zhang George F. Gao Weiwei Zhai Fengcai Zhu Zihe Rao Xiangxi Wang Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
description	Echovirus 30 (E30) belongs to the Enterovirus-B group and causes aseptic meningitis in humans. Here, the authors present the cryo-EM structures of the E30 E-particle, A-particle and the mature virion, as well as structures of E30 in complex with its receptor FcRn and CD55, and furthermore they describe a structure-based algorithm that allows the prediction of EV receptor usage.
format	article
author	Kang Wang Ling Zhu Yao Sun Minhao Li Xin Zhao Lunbiao Cui Li Zhang George F. Gao Weiwei Zhai Fengcai Zhu Zihe Rao Xiangxi Wang
author_facet	Kang Wang Ling Zhu Yao Sun Minhao Li Xin Zhao Lunbiao Cui Li Zhang George F. Gao Weiwei Zhai Fengcai Zhu Zihe Rao Xiangxi Wang
author_sort	Kang Wang
title	Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
title_short	Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
title_full	Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
title_fullStr	Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
title_full_unstemmed	Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
title_sort	structures of echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/56c313c3a4bd4f1b8aea3e2cd8500956
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Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage

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