NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons

AgRP-expressing neurons regulate feeding, glucose homeostasis and locomotor activity, but the neurotransmitters that mediate these effects are unclear. Here the authors show that neuropeptide Y in these neurons regulates rapid feeding responses and insulin sensitivity, but not locomotor activity.

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Autores principales:	Linda Engström Ruud, Mafalda M. A. Pereira, Alain J. de Solis, Henning Fenselau, Jens C. Brüning
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/56c5b96e122a451db613e7cb36275234
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spelling	oai:doaj.org-article:56c5b96e122a451db613e7cb362752342021-12-02T15:39:12ZNPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons10.1038/s41467-020-14291-32041-1723https://doaj.org/article/56c5b96e122a451db613e7cb362752342020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14291-3https://doaj.org/toc/2041-1723AgRP-expressing neurons regulate feeding, glucose homeostasis and locomotor activity, but the neurotransmitters that mediate these effects are unclear. Here the authors show that neuropeptide Y in these neurons regulates rapid feeding responses and insulin sensitivity, but not locomotor activity.Linda Engström RuudMafalda M. A. PereiraAlain J. de SolisHenning FenselauJens C. BrüningNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Linda Engström Ruud Mafalda M. A. Pereira Alain J. de Solis Henning Fenselau Jens C. Brüning NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
description	AgRP-expressing neurons regulate feeding, glucose homeostasis and locomotor activity, but the neurotransmitters that mediate these effects are unclear. Here the authors show that neuropeptide Y in these neurons regulates rapid feeding responses and insulin sensitivity, but not locomotor activity.
format	article
author	Linda Engström Ruud Mafalda M. A. Pereira Alain J. de Solis Henning Fenselau Jens C. Brüning
author_facet	Linda Engström Ruud Mafalda M. A. Pereira Alain J. de Solis Henning Fenselau Jens C. Brüning
author_sort	Linda Engström Ruud
title	NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
title_short	NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
title_full	NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
title_fullStr	NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
title_full_unstemmed	NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
title_sort	npy mediates the rapid feeding and glucose metabolism regulatory functions of agrp neurons
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/56c5b96e122a451db613e7cb36275234
work_keys_str_mv	AT lindaengstromruud npymediatestherapidfeedingandglucosemetabolismregulatoryfunctionsofagrpneurons AT mafaldamapereira npymediatestherapidfeedingandglucosemetabolismregulatoryfunctionsofagrpneurons AT alainjdesolis npymediatestherapidfeedingandglucosemetabolismregulatoryfunctionsofagrpneurons AT henningfenselau npymediatestherapidfeedingandglucosemetabolismregulatoryfunctionsofagrpneurons AT jenscbruning npymediatestherapidfeedingandglucosemetabolismregulatoryfunctionsofagrpneurons
_version_	1718385988491804672

NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons

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