NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
AgRP-expressing neurons regulate feeding, glucose homeostasis and locomotor activity, but the neurotransmitters that mediate these effects are unclear. Here the authors show that neuropeptide Y in these neurons regulates rapid feeding responses and insulin sensitivity, but not locomotor activity.
Guardado en:
Autores principales: | Linda Engström Ruud, Mafalda M. A. Pereira, Alain J. de Solis, Henning Fenselau, Jens C. Brüning |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/56c5b96e122a451db613e7cb36275234 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo
por: Yanbin Dong, et al.
Publicado: (2021) -
Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding
por: Yong Han, et al.
Publicado: (2021) -
DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice
por: Harry MacKay, et al.
Publicado: (2019) -
Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
por: Isadora C. Furigo, et al.
Publicado: (2019) -
Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
por: Bora Lee, et al.
Publicado: (2018)