Analysis at the single-cell level indicates an important role of heterogeneous global DNA methylation status on the progression of lung adenocarcinoma
Abstract Aberrant DNA modifications affect the tumorigenesis and progression of lung cancer. However, the global methylation status of tumor cells and the heterogeneous methylation status of cells within the same tumor need further study. We used publicly available single-cell RNAseq data to investi...
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Autores principales: | Quan-Fang Chen, Han Gao, Qing-Yun Pan, Ying-Ju Wang, Xiao-Ning Zhong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/56ccb5b3517e4e4187a760697307ad60 |
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