Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J

Despite being known for more than 50 years, yuzurimine-type alkaloids have not been accessed by total synthesis. Here, the authors report the first enantioselective total synthesis of (+)-Caldaphnidine J, a highly complex yuzurimine-type Daphniphyllum alkaloid.

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Autores principales: Lian-Dong Guo, Yan Zhang, Jingping Hu, Chengqing Ning, Heyifei Fu, Yuye Chen, Jing Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/56d24c15a8254f91bc01a6357360c039
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spelling oai:doaj.org-article:56d24c15a8254f91bc01a6357360c0392021-12-02T18:37:05ZAsymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J10.1038/s41467-020-17350-x2041-1723https://doaj.org/article/56d24c15a8254f91bc01a6357360c0392020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17350-xhttps://doaj.org/toc/2041-1723Despite being known for more than 50 years, yuzurimine-type alkaloids have not been accessed by total synthesis. Here, the authors report the first enantioselective total synthesis of (+)-Caldaphnidine J, a highly complex yuzurimine-type Daphniphyllum alkaloid.Lian-Dong GuoYan ZhangJingping HuChengqing NingHeyifei FuYuye ChenJing XuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lian-Dong Guo
Yan Zhang
Jingping Hu
Chengqing Ning
Heyifei Fu
Yuye Chen
Jing Xu
Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J
description Despite being known for more than 50 years, yuzurimine-type alkaloids have not been accessed by total synthesis. Here, the authors report the first enantioselective total synthesis of (+)-Caldaphnidine J, a highly complex yuzurimine-type Daphniphyllum alkaloid.
format article
author Lian-Dong Guo
Yan Zhang
Jingping Hu
Chengqing Ning
Heyifei Fu
Yuye Chen
Jing Xu
author_facet Lian-Dong Guo
Yan Zhang
Jingping Hu
Chengqing Ning
Heyifei Fu
Yuye Chen
Jing Xu
author_sort Lian-Dong Guo
title Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J
title_short Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J
title_full Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J
title_fullStr Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J
title_full_unstemmed Asymmetric total synthesis of yuzurimine-type Daphniphyllum alkaloid (+)-caldaphnidine J
title_sort asymmetric total synthesis of yuzurimine-type daphniphyllum alkaloid (+)-caldaphnidine j
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/56d24c15a8254f91bc01a6357360c039
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