Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance atherosclerotic plaque formation through delivery of...

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Autores principales:	Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b
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spelling	oai:doaj.org-article:56d869ba2dc54e5c8b181fd48b5df87b2021-12-02T15:37:17ZNeutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium10.1038/s41467-019-14043-y2041-1723https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14043-yhttps://doaj.org/toc/2041-1723The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance atherosclerotic plaque formation through delivery of miR-155.Ingrid GomezBen WardCeline SouilholChiara RecartiMark AriaansJessica JohnstonAmanda BurnettMarwa MahmoudLe Anh LuongLaura WestMerete LongSion ParryRachel WoodsCarl HulstonBirke BenedikterChiara NiespoloRohit BazazSheila FrancisEndre Kiss-TothMarc van ZandvoortAndreas SchoberPaul HellewellPaul C. EvansVictoria RidgerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ingrid Gomez Ben Ward Celine Souilhol Chiara Recarti Mark Ariaans Jessica Johnston Amanda Burnett Marwa Mahmoud Le Anh Luong Laura West Merete Long Sion Parry Rachel Woods Carl Hulston Birke Benedikter Chiara Niespolo Rohit Bazaz Sheila Francis Endre Kiss-Toth Marc van Zandvoort Andreas Schober Paul Hellewell Paul C. Evans Victoria Ridger Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
description	The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance atherosclerotic plaque formation through delivery of miR-155.
format	article
author	Ingrid Gomez Ben Ward Celine Souilhol Chiara Recarti Mark Ariaans Jessica Johnston Amanda Burnett Marwa Mahmoud Le Anh Luong Laura West Merete Long Sion Parry Rachel Woods Carl Hulston Birke Benedikter Chiara Niespolo Rohit Bazaz Sheila Francis Endre Kiss-Toth Marc van Zandvoort Andreas Schober Paul Hellewell Paul C. Evans Victoria Ridger
author_facet	Ingrid Gomez Ben Ward Celine Souilhol Chiara Recarti Mark Ariaans Jessica Johnston Amanda Burnett Marwa Mahmoud Le Anh Luong Laura West Merete Long Sion Parry Rachel Woods Carl Hulston Birke Benedikter Chiara Niespolo Rohit Bazaz Sheila Francis Endre Kiss-Toth Marc van Zandvoort Andreas Schober Paul Hellewell Paul C. Evans Victoria Ridger
author_sort	Ingrid Gomez
title	Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
title_short	Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
title_full	Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
title_fullStr	Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
title_full_unstemmed	Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
title_sort	neutrophil microvesicles drive atherosclerosis by delivering mir-155 to atheroprone endothelium
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b
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Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

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