Immune responses induced by different vaccine platforms against coronavirus disease-19

There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to manipulate the appearance of a pathogen. Subsequently pathogens such as viruses and bacteria often demonst...

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Autores principales: Eknath D. Ahire, Sanjay J. Kshirsagar
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Lenguaje:EN
Publicado: Open Exploration Publishing Inc. 2021
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spelling oai:doaj.org-article:56da70bd7e6c465888bb635266c62c672021-11-24T06:24:15ZImmune responses induced by different vaccine platforms against coronavirus disease-1910.37349/ei.2021.000162768-6655https://doaj.org/article/56da70bd7e6c465888bb635266c62c672021-10-01T00:00:00Zhttps://www.explorationpub.com/Journals/ei/Article/100316https://doaj.org/toc/2768-6655There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to manipulate the appearance of a pathogen. Subsequently pathogens such as viruses and bacteria often demonstrate of multiple copies of ligands on their surfaces, the immune system is predominantly sensitive towards multivalent presentations of antigens. Consequently, when designing a vaccine, it is beneficial to garnish a nanostructured surface with multiple copies of an antigen so it can effectively act as an immune booster. Different methods are there for the development of the vaccine, from them most of the techniques are well developed and reported and some of in the developing state. This review focuses primarily on cellular and non-cellular vaccines, the whole cells or cellular proteins either as the source of antigens or the platform in which to deliver the antigens. Purpose of this review, understand and discussion on the various vaccine platforms which will contribute noteworthy information to vaccine research and development (R and D).Eknath D. AhireSanjay J. KshirsagarOpen Exploration Publishing Inc.articlevaccineplatformimmune responsevaccinationdevelopmentImmunologic diseases. AllergyRC581-607ENExploration of Immunology, Vol 1, Iss 4, Pp 243-257 (2021)
institution DOAJ
collection DOAJ
language EN
topic vaccine
platform
immune response
vaccination
development
Immunologic diseases. Allergy
RC581-607
spellingShingle vaccine
platform
immune response
vaccination
development
Immunologic diseases. Allergy
RC581-607
Eknath D. Ahire
Sanjay J. Kshirsagar
Immune responses induced by different vaccine platforms against coronavirus disease-19
description There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to manipulate the appearance of a pathogen. Subsequently pathogens such as viruses and bacteria often demonstrate of multiple copies of ligands on their surfaces, the immune system is predominantly sensitive towards multivalent presentations of antigens. Consequently, when designing a vaccine, it is beneficial to garnish a nanostructured surface with multiple copies of an antigen so it can effectively act as an immune booster. Different methods are there for the development of the vaccine, from them most of the techniques are well developed and reported and some of in the developing state. This review focuses primarily on cellular and non-cellular vaccines, the whole cells or cellular proteins either as the source of antigens or the platform in which to deliver the antigens. Purpose of this review, understand and discussion on the various vaccine platforms which will contribute noteworthy information to vaccine research and development (R and D).
format article
author Eknath D. Ahire
Sanjay J. Kshirsagar
author_facet Eknath D. Ahire
Sanjay J. Kshirsagar
author_sort Eknath D. Ahire
title Immune responses induced by different vaccine platforms against coronavirus disease-19
title_short Immune responses induced by different vaccine platforms against coronavirus disease-19
title_full Immune responses induced by different vaccine platforms against coronavirus disease-19
title_fullStr Immune responses induced by different vaccine platforms against coronavirus disease-19
title_full_unstemmed Immune responses induced by different vaccine platforms against coronavirus disease-19
title_sort immune responses induced by different vaccine platforms against coronavirus disease-19
publisher Open Exploration Publishing Inc.
publishDate 2021
url https://doaj.org/article/56da70bd7e6c465888bb635266c62c67
work_keys_str_mv AT eknathdahire immuneresponsesinducedbydifferentvaccineplatformsagainstcoronavirusdisease19
AT sanjayjkshirsagar immuneresponsesinducedbydifferentvaccineplatformsagainstcoronavirusdisease19
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