Immune responses induced by different vaccine platforms against coronavirus disease-19
There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to manipulate the appearance of a pathogen. Subsequently pathogens such as viruses and bacteria often demonst...
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Open Exploration Publishing Inc.
2021
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oai:doaj.org-article:56da70bd7e6c465888bb635266c62c672021-11-24T06:24:15ZImmune responses induced by different vaccine platforms against coronavirus disease-1910.37349/ei.2021.000162768-6655https://doaj.org/article/56da70bd7e6c465888bb635266c62c672021-10-01T00:00:00Zhttps://www.explorationpub.com/Journals/ei/Article/100316https://doaj.org/toc/2768-6655There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to manipulate the appearance of a pathogen. Subsequently pathogens such as viruses and bacteria often demonstrate of multiple copies of ligands on their surfaces, the immune system is predominantly sensitive towards multivalent presentations of antigens. Consequently, when designing a vaccine, it is beneficial to garnish a nanostructured surface with multiple copies of an antigen so it can effectively act as an immune booster. Different methods are there for the development of the vaccine, from them most of the techniques are well developed and reported and some of in the developing state. This review focuses primarily on cellular and non-cellular vaccines, the whole cells or cellular proteins either as the source of antigens or the platform in which to deliver the antigens. Purpose of this review, understand and discussion on the various vaccine platforms which will contribute noteworthy information to vaccine research and development (R and D).Eknath D. AhireSanjay J. KshirsagarOpen Exploration Publishing Inc.articlevaccineplatformimmune responsevaccinationdevelopmentImmunologic diseases. AllergyRC581-607ENExploration of Immunology, Vol 1, Iss 4, Pp 243-257 (2021) |
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vaccine platform immune response vaccination development Immunologic diseases. Allergy RC581-607 |
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vaccine platform immune response vaccination development Immunologic diseases. Allergy RC581-607 Eknath D. Ahire Sanjay J. Kshirsagar Immune responses induced by different vaccine platforms against coronavirus disease-19 |
description |
There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to manipulate the appearance of a pathogen. Subsequently pathogens such as viruses and bacteria often demonstrate of multiple copies of ligands on their surfaces, the immune system is predominantly sensitive towards multivalent presentations of antigens. Consequently, when designing a vaccine, it is beneficial to garnish a nanostructured surface with multiple copies of an antigen so it can effectively act as an immune booster. Different methods are there for the development of the vaccine, from them most of the techniques are well developed and reported and some of in the developing state. This review focuses primarily on cellular and non-cellular vaccines, the whole cells or cellular proteins either as the source of antigens or the platform in which to deliver the antigens. Purpose of this review, understand and discussion on the various vaccine platforms which will contribute noteworthy information to vaccine research and development (R and D). |
format |
article |
author |
Eknath D. Ahire Sanjay J. Kshirsagar |
author_facet |
Eknath D. Ahire Sanjay J. Kshirsagar |
author_sort |
Eknath D. Ahire |
title |
Immune responses induced by different vaccine platforms against coronavirus disease-19 |
title_short |
Immune responses induced by different vaccine platforms against coronavirus disease-19 |
title_full |
Immune responses induced by different vaccine platforms against coronavirus disease-19 |
title_fullStr |
Immune responses induced by different vaccine platforms against coronavirus disease-19 |
title_full_unstemmed |
Immune responses induced by different vaccine platforms against coronavirus disease-19 |
title_sort |
immune responses induced by different vaccine platforms against coronavirus disease-19 |
publisher |
Open Exploration Publishing Inc. |
publishDate |
2021 |
url |
https://doaj.org/article/56da70bd7e6c465888bb635266c62c67 |
work_keys_str_mv |
AT eknathdahire immuneresponsesinducedbydifferentvaccineplatformsagainstcoronavirusdisease19 AT sanjayjkshirsagar immuneresponsesinducedbydifferentvaccineplatformsagainstcoronavirusdisease19 |
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1718415913553756160 |