State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection

The paper describes the details of electron-microscopic study of the intima of blood vessels of the umbilical cord, produced during childbirth from women undergoing in the 111 trimester of gestation cytomegalovirus infection. It was found that the endothelial cells of the umbilical cord arteries the...

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Autor principal:	N. N. Dorofienko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	cytomegalovirus infection umbilical cord artery endothelial apoptosis Science Q
Acceso en línea:	https://doaj.org/article/56de1d6cf6bc40e0869a9deba224184c
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spelling	oai:doaj.org-article:56de1d6cf6bc40e0869a9deba224184c2021-11-23T06:14:31ZState of vascular wall of umbilical arteries of fetus at cytomegalovirus infection2541-94202587-9596https://doaj.org/article/56de1d6cf6bc40e0869a9deba224184c2015-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/4https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The paper describes the details of electron-microscopic study of the intima of blood vessels of the umbilical cord, produced during childbirth from women undergoing in the 111 trimester of gestation cytomegalovirus infection. It was found that the endothelial cells of the umbilical cord arteries there is a reduction of protein-synthetic and proliferative their functions, as well as the introduction of endothelial apoptosis, with the characteristics of manifestations, expressed degenerative and destructive changes in the cell, the loss of cell-cell contacts, intussusception plasmolemma, the destruction of the cytoskeleton, chromatin condensation, nuclear fragmentation and the formation of apoptotic bodies. Revealed changes in the endothelium may contribute dyscirculatory disorders in arterial vessels of the umbilical cord and to initiate the development of spasm of the arteries. Modification of these functions studied gestational tissues obviously contributes to the reduction of the intensity of the blood flow of the fetus, the development of intrauterine hypoxia.N. N. DorofienkoScientific Сentre for Family Health and Human Reproduction Problemsarticlecytomegalovirus infectionumbilicalcord artery endothelialapoptosisScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 18-23 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	cytomegalovirus infection umbilical cord artery endothelial apoptosis Science Q
spellingShingle	cytomegalovirus infection umbilical cord artery endothelial apoptosis Science Q N. N. Dorofienko State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
description	The paper describes the details of electron-microscopic study of the intima of blood vessels of the umbilical cord, produced during childbirth from women undergoing in the 111 trimester of gestation cytomegalovirus infection. It was found that the endothelial cells of the umbilical cord arteries there is a reduction of protein-synthetic and proliferative their functions, as well as the introduction of endothelial apoptosis, with the characteristics of manifestations, expressed degenerative and destructive changes in the cell, the loss of cell-cell contacts, intussusception plasmolemma, the destruction of the cytoskeleton, chromatin condensation, nuclear fragmentation and the formation of apoptotic bodies. Revealed changes in the endothelium may contribute dyscirculatory disorders in arterial vessels of the umbilical cord and to initiate the development of spasm of the arteries. Modification of these functions studied gestational tissues obviously contributes to the reduction of the intensity of the blood flow of the fetus, the development of intrauterine hypoxia.
format	article
author	N. N. Dorofienko
author_facet	N. N. Dorofienko
author_sort	N. N. Dorofienko
title	State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
title_short	State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
title_full	State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
title_fullStr	State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
title_full_unstemmed	State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
title_sort	state of vascular wall of umbilical arteries of fetus at cytomegalovirus infection
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/56de1d6cf6bc40e0869a9deba224184c
work_keys_str_mv	AT nndorofienko stateofvascularwallofumbilicalarteriesoffetusatcytomegalovirusinfection
_version_	1718417070766424064

State of vascular wall of umbilical arteries of fetus at cytomegalovirus infection

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