A nonenzymatic method for cleaving polysaccharides to yield oligosaccharides for structural analysis

While mass spectrometry-based proteomics largely relies on digesting proteins into peptides, there is no equivalent strategy for polysaccharide analysis. Here, the authors develop a chemical approach to break down poly- into oligosaccharides and present a workflow to identify polysaccharides by olig...

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Bibliographic Details
Main Authors: Matthew J. Amicucci, Eshani Nandita, Ace G. Galermo, Juan Jose Castillo, Siyu Chen, Dayoung Park, Jennifer T. Smilowitz, J. Bruce German, David A. Mills, Carlito B. Lebrilla
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/56e858fbf541481aa828e4e37d9df50a
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