A nonenzymatic method for cleaving polysaccharides to yield oligosaccharides for structural analysis
While mass spectrometry-based proteomics largely relies on digesting proteins into peptides, there is no equivalent strategy for polysaccharide analysis. Here, the authors develop a chemical approach to break down poly- into oligosaccharides and present a workflow to identify polysaccharides by olig...
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Main Authors: | Matthew J. Amicucci, Eshani Nandita, Ace G. Galermo, Juan Jose Castillo, Siyu Chen, Dayoung Park, Jennifer T. Smilowitz, J. Bruce German, David A. Mills, Carlito B. Lebrilla |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/56e858fbf541481aa828e4e37d9df50a |
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