SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway.
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Nature Portfolio
2018
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oai:doaj.org-article:5703e4bf0087489eaecd2013c1eb52d72021-12-02T14:39:10ZSIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway10.1038/s41467-017-02586-x2041-1723https://doaj.org/article/5703e4bf0087489eaecd2013c1eb52d72018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02586-xhttps://doaj.org/toc/2041-1723Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway.Irene Santos-BarriopedroLaia Bosch-PreseguéAnna Marazuela-DuqueCarolina de la TorreCarlota ColomerBerta N. VazquezThomas FuhrmannBárbara Martínez-PastorWenfu LuThomas BraunEva BoberThomas JenuweinLourdes SerranoManel EstellerZhenbang ChenSilvia Barceló-BatlloriRaúl MostoslavskyLluis EspinosaAlejandro VaqueroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Irene Santos-Barriopedro Laia Bosch-Presegué Anna Marazuela-Duque Carolina de la Torre Carlota Colomer Berta N. Vazquez Thomas Fuhrmann Bárbara Martínez-Pastor Wenfu Lu Thomas Braun Eva Bober Thomas Jenuwein Lourdes Serrano Manel Esteller Zhenbang Chen Silvia Barceló-Batllori Raúl Mostoslavsky Lluis Espinosa Alejandro Vaquero SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway |
description |
Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway. |
format |
article |
author |
Irene Santos-Barriopedro Laia Bosch-Presegué Anna Marazuela-Duque Carolina de la Torre Carlota Colomer Berta N. Vazquez Thomas Fuhrmann Bárbara Martínez-Pastor Wenfu Lu Thomas Braun Eva Bober Thomas Jenuwein Lourdes Serrano Manel Esteller Zhenbang Chen Silvia Barceló-Batllori Raúl Mostoslavsky Lluis Espinosa Alejandro Vaquero |
author_facet |
Irene Santos-Barriopedro Laia Bosch-Presegué Anna Marazuela-Duque Carolina de la Torre Carlota Colomer Berta N. Vazquez Thomas Fuhrmann Bárbara Martínez-Pastor Wenfu Lu Thomas Braun Eva Bober Thomas Jenuwein Lourdes Serrano Manel Esteller Zhenbang Chen Silvia Barceló-Batllori Raúl Mostoslavsky Lluis Espinosa Alejandro Vaquero |
author_sort |
Irene Santos-Barriopedro |
title |
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway |
title_short |
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway |
title_full |
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway |
title_fullStr |
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway |
title_full_unstemmed |
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway |
title_sort |
sirt6-dependent cysteine monoubiquitination in the pre-set domain of suv39h1 regulates the nf-κb pathway |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/5703e4bf0087489eaecd2013c1eb52d7 |
work_keys_str_mv |
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