SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway

Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway.

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Autores principales: Irene Santos-Barriopedro, Laia Bosch-Presegué, Anna Marazuela-Duque, Carolina de la Torre, Carlota Colomer, Berta N. Vazquez, Thomas Fuhrmann, Bárbara Martínez-Pastor, Wenfu Lu, Thomas Braun, Eva Bober, Thomas Jenuwein, Lourdes Serrano, Manel Esteller, Zhenbang Chen, Silvia Barceló-Batllori, Raúl Mostoslavsky, Lluis Espinosa, Alejandro Vaquero
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5703e4bf0087489eaecd2013c1eb52d7
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spelling oai:doaj.org-article:5703e4bf0087489eaecd2013c1eb52d72021-12-02T14:39:10ZSIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway10.1038/s41467-017-02586-x2041-1723https://doaj.org/article/5703e4bf0087489eaecd2013c1eb52d72018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02586-xhttps://doaj.org/toc/2041-1723Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway.Irene Santos-BarriopedroLaia Bosch-PreseguéAnna Marazuela-DuqueCarolina de la TorreCarlota ColomerBerta N. VazquezThomas FuhrmannBárbara Martínez-PastorWenfu LuThomas BraunEva BoberThomas JenuweinLourdes SerranoManel EstellerZhenbang ChenSilvia Barceló-BatlloriRaúl MostoslavskyLluis EspinosaAlejandro VaqueroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Irene Santos-Barriopedro
Laia Bosch-Presegué
Anna Marazuela-Duque
Carolina de la Torre
Carlota Colomer
Berta N. Vazquez
Thomas Fuhrmann
Bárbara Martínez-Pastor
Wenfu Lu
Thomas Braun
Eva Bober
Thomas Jenuwein
Lourdes Serrano
Manel Esteller
Zhenbang Chen
Silvia Barceló-Batllori
Raúl Mostoslavsky
Lluis Espinosa
Alejandro Vaquero
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
description Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κB pathway.
format article
author Irene Santos-Barriopedro
Laia Bosch-Presegué
Anna Marazuela-Duque
Carolina de la Torre
Carlota Colomer
Berta N. Vazquez
Thomas Fuhrmann
Bárbara Martínez-Pastor
Wenfu Lu
Thomas Braun
Eva Bober
Thomas Jenuwein
Lourdes Serrano
Manel Esteller
Zhenbang Chen
Silvia Barceló-Batllori
Raúl Mostoslavsky
Lluis Espinosa
Alejandro Vaquero
author_facet Irene Santos-Barriopedro
Laia Bosch-Presegué
Anna Marazuela-Duque
Carolina de la Torre
Carlota Colomer
Berta N. Vazquez
Thomas Fuhrmann
Bárbara Martínez-Pastor
Wenfu Lu
Thomas Braun
Eva Bober
Thomas Jenuwein
Lourdes Serrano
Manel Esteller
Zhenbang Chen
Silvia Barceló-Batllori
Raúl Mostoslavsky
Lluis Espinosa
Alejandro Vaquero
author_sort Irene Santos-Barriopedro
title SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
title_short SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
title_full SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
title_fullStr SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
title_full_unstemmed SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway
title_sort sirt6-dependent cysteine monoubiquitination in the pre-set domain of suv39h1 regulates the nf-κb pathway
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5703e4bf0087489eaecd2013c1eb52d7
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