The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts

Abstract Excessive bone resorption by osteoclasts (OCs) can result in serious clinical outcomes, including bone loss that may weaken skeletal or periodontal strength. Proper bone homeostasis and skeletal strength are maintained by balancing OC function with the bone-forming function of osteoblasts....

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Autores principales: Hyunsoo Kim, Matthew C. Walsh, Noriko Takegahara, Sarah A. Middleton, Hong-In Shin, Junhyong Kim, Yongwon Choi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/570b4bebfc7a4da78d4458ebaf52f774
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