A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype

Lance C Dalleck,1,3 Gary P Van Guilder,2,3 Tara B Richardson,1 Donald L Bredle,3 Jeffrey M Janot31Recreation, Exercise, and Sport Science Department, Western State Colorado University, Gunnison, CO, USA; 2Department of Health and Nutritional Sciences, South Dakota State University, Brookings, SD, U...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Dalleck LC, Van Guilder GP, Richardson TB, Bredle DL, Janot JM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/5712b55b971446a0835954af5dba4047
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5712b55b971446a0835954af5dba4047
record_format	dspace
spelling	oai:doaj.org-article:5712b55b971446a0835954af5dba40472021-12-02T00:04:23ZA community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype1178-7007https://doaj.org/article/5712b55b971446a0835954af5dba40472014-08-01T00:00:00Zhttp://www.dovepress.com/a-community-based-exercise-intervention-transitions-metabolically-abno-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Lance C Dalleck,1,3 Gary P Van Guilder,2,3 Tara B Richardson,1 Donald L Bredle,3 Jeffrey M Janot31Recreation, Exercise, and Sport Science Department, Western State Colorado University, Gunnison, CO, USA; 2Department of Health and Nutritional Sciences, South Dakota State University, Brookings, SD, USA; 3Department of Kinesiology, University of Wisconsin-Eau Claire, Eau Claire, WI, USABackground: Lower habitual physical activity and poor cardiorespiratory fitness are common features of the metabolically abnormal obese (MAO) phenotype that contribute to increased cardiovascular disease risk. The aims of the present study were to determine 1) whether community-based exercise training transitions MAO adults to metabolically healthy, and 2) whether the odds of transition to metabolically healthy were larger for obese individuals who performed higher volumes of exercise and/or experienced greater increases in fitness.Methods and results: Metabolic syndrome components were measured in 332 adults (190 women, 142 men) before and after a supervised 14-week community-based exercise program designed to reduce cardiometabolic risk factors. Obese (body mass index ≥30 kg · m2) adults with two to four metabolic syndrome components were classified as MAO, whereas those with no or one component were classified as metabolically healthy but obese (MHO). After community exercise, 27/68 (40%) MAO individuals (P<0.05) transitioned to metabolically healthy, increasing the total number of MHO persons by 73% (from 37 to 64). Compared with the lowest quartiles of relative energy expenditure and change in fitness, participants in the highest quartiles were 11.6 (95% confidence interval: 2.1–65.4; P<0.05) and 7.5 (95% confidence interval: 1.5–37.5; P<0.05) times more likely to transition from MAO to MHO, respectively.Conclusion: Community-based exercise transitions MAO adults to metabolically healthy. MAO adults who engaged in higher volumes of exercise and experienced the greatest increase in fitness were significantly more likely to become metabolically healthy. Community exercise may be an effective model for primary prevention of cardiovascular disease.Keywords: exercise, obesity, prevention, risk factorsDalleck LCVan Guilder GPRichardson TBBredle DLJanot JMDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2014, Iss default, Pp 369-380 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Dalleck LC Van Guilder GP Richardson TB Bredle DL Janot JM A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
description	Lance C Dalleck,1,3 Gary P Van Guilder,2,3 Tara B Richardson,1 Donald L Bredle,3 Jeffrey M Janot31Recreation, Exercise, and Sport Science Department, Western State Colorado University, Gunnison, CO, USA; 2Department of Health and Nutritional Sciences, South Dakota State University, Brookings, SD, USA; 3Department of Kinesiology, University of Wisconsin-Eau Claire, Eau Claire, WI, USABackground: Lower habitual physical activity and poor cardiorespiratory fitness are common features of the metabolically abnormal obese (MAO) phenotype that contribute to increased cardiovascular disease risk. The aims of the present study were to determine 1) whether community-based exercise training transitions MAO adults to metabolically healthy, and 2) whether the odds of transition to metabolically healthy were larger for obese individuals who performed higher volumes of exercise and/or experienced greater increases in fitness.Methods and results: Metabolic syndrome components were measured in 332 adults (190 women, 142 men) before and after a supervised 14-week community-based exercise program designed to reduce cardiometabolic risk factors. Obese (body mass index ≥30 kg · m2) adults with two to four metabolic syndrome components were classified as MAO, whereas those with no or one component were classified as metabolically healthy but obese (MHO). After community exercise, 27/68 (40%) MAO individuals (P<0.05) transitioned to metabolically healthy, increasing the total number of MHO persons by 73% (from 37 to 64). Compared with the lowest quartiles of relative energy expenditure and change in fitness, participants in the highest quartiles were 11.6 (95% confidence interval: 2.1–65.4; P<0.05) and 7.5 (95% confidence interval: 1.5–37.5; P<0.05) times more likely to transition from MAO to MHO, respectively.Conclusion: Community-based exercise transitions MAO adults to metabolically healthy. MAO adults who engaged in higher volumes of exercise and experienced the greatest increase in fitness were significantly more likely to become metabolically healthy. Community exercise may be an effective model for primary prevention of cardiovascular disease.Keywords: exercise, obesity, prevention, risk factors
format	article
author	Dalleck LC Van Guilder GP Richardson TB Bredle DL Janot JM
author_facet	Dalleck LC Van Guilder GP Richardson TB Bredle DL Janot JM
author_sort	Dalleck LC
title	A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
title_short	A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
title_full	A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
title_fullStr	A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
title_full_unstemmed	A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
title_sort	community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/5712b55b971446a0835954af5dba4047
work_keys_str_mv	AT dallecklc acommunitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT vanguildergp acommunitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT richardsontb acommunitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT bredledl acommunitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT janotjm acommunitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT dallecklc communitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT vanguildergp communitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT richardsontb communitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT bredledl communitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype AT janotjm communitybasedexerciseinterventiontransitionsmetabolicallyabnormalobeseadultstoametabolicallyhealthyobesephenotype
_version_	1718403929538035712

A community-based exercise intervention transitions metabolically abnormal obese adults to a metabolically healthy obese phenotype

Ejemplares similares