Clinical Severity of Visceral Leishmaniasis Is Associated with Changes in Immunoglobulin G Fc N-Glycosylation

Clinical Severity of Visceral Leishmaniasis Is Associated with Changes in Immunoglobulin G Fc N-Glycosylation

ABSTRACT  Visceral leishmaniasis (VL) has a high fatality rate if not treated; nevertheless, the majority of human infections with the causative agent, Leishmania infantum chagasi, are asymptomatic. Although VL patients often present with increased levels of serum immunoglobulins, the contribution o...

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Main Authors: Luiz Gustavo Gardinassi, Viktoria Dotz, Agnes Hipgrave Ederveen, Roque Pacheco de Almeida, Carlos Henrique Nery Costa, Dorcas Lamounier Costa, Amélia Ribeiro de Jesus, Oleg A. Mayboroda, Gustavo Rocha Garcia, Manfred Wuhrer, Isabel Kinney Ferreira de Miranda Santos
Format: article
Language:EN
Published: American Society for Microbiology 2014
Subjects:
Microbiology
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Online Access:https://doaj.org/article/5717c5e5529843b59cce8767a8243131
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https://doaj.org/article/5717c5e5529843b59cce8767a8243131

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