Endometrial hyperplasia: without atypia and with atypia

The article analyzes and presents data for the last 70 years from the PubMed database on endometrial hyperplasia (EH), which is one of the leaders in the structure of gynecological diseases and the main predictor of endometrial cancer (EC). The chronicle of the EH classification is highlighted with...

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Autores principales:	Maksim A. Sabantsev, Svetlana V. Shramko, Vladimir G. Levchenko, Oleg A. Volkov, Tatyana V. Tretyakova
Formato:	article
Lenguaje:	RU
Publicado:	IP Berlin A.V. 2021
Materias:	adenomatosis endometrial cancer endometrial hyperplasia glandular intraepithelial neoplasia hysteroscopy predictors of endometrial cancer reproducibility of the diagnosis tamoxifen Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/5720f9cf9c2e46548e80c415663b46ec
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spelling	oai:doaj.org-article:5720f9cf9c2e46548e80c415663b46ec2021-12-02T19:22:24ZEndometrial hyperplasia: without atypia and with atypia2079-56962079-583110.26442/20795696.2021.1.200666https://doaj.org/article/5720f9cf9c2e46548e80c415663b46ec2021-03-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/63625/46623https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831The article analyzes and presents data for the last 70 years from the PubMed database on endometrial hyperplasia (EH), which is one of the leaders in the structure of gynecological diseases and the main predictor of endometrial cancer (EC). The chronicle of the EH classification is highlighted with a focus on changing the designation and relevance of adenomatous EH. It is shown how the current classification of EH, due to the fact that a large number of synonyms is limited by two options, allows to maximize the reproducibility of the diagnosis, improve the interaction of the obstetrician-gynecologist with the pathologist and reduce the treatment inefficiency. The results of modern studies on the prevalence and risk factors of EH and EC differ from previously accepted ones and destroy the Bohman triad. The risks of EH development with tamoxifen and menopausal hormone therapy are determined. The data of current research methods aimed at the diagnosis of EH and EC are indicated. The differences in etiopathogenesis, prevalence, diagnosis, risk factors for development and progression to the malignant process presented in the review represent two types of EH (without atypia and with atypia) as completely different endometrial diseases included in the same classification.Maksim A. SabantsevSvetlana V. ShramkoVladimir G. LevchenkoOleg A. VolkovTatyana V. TretyakovaIP Berlin A.V. articleadenomatosisendometrial cancerendometrial hyperplasiaglandular intraepithelial neoplasiahysteroscopypredictors of endometrial cancerreproducibility of the diagnosistamoxifenGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 1, Pp 18-24 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	adenomatosis endometrial cancer endometrial hyperplasia glandular intraepithelial neoplasia hysteroscopy predictors of endometrial cancer reproducibility of the diagnosis tamoxifen Gynecology and obstetrics RG1-991
spellingShingle	adenomatosis endometrial cancer endometrial hyperplasia glandular intraepithelial neoplasia hysteroscopy predictors of endometrial cancer reproducibility of the diagnosis tamoxifen Gynecology and obstetrics RG1-991 Maksim A. Sabantsev Svetlana V. Shramko Vladimir G. Levchenko Oleg A. Volkov Tatyana V. Tretyakova Endometrial hyperplasia: without atypia and with atypia
description	The article analyzes and presents data for the last 70 years from the PubMed database on endometrial hyperplasia (EH), which is one of the leaders in the structure of gynecological diseases and the main predictor of endometrial cancer (EC). The chronicle of the EH classification is highlighted with a focus on changing the designation and relevance of adenomatous EH. It is shown how the current classification of EH, due to the fact that a large number of synonyms is limited by two options, allows to maximize the reproducibility of the diagnosis, improve the interaction of the obstetrician-gynecologist with the pathologist and reduce the treatment inefficiency. The results of modern studies on the prevalence and risk factors of EH and EC differ from previously accepted ones and destroy the Bohman triad. The risks of EH development with tamoxifen and menopausal hormone therapy are determined. The data of current research methods aimed at the diagnosis of EH and EC are indicated. The differences in etiopathogenesis, prevalence, diagnosis, risk factors for development and progression to the malignant process presented in the review represent two types of EH (without atypia and with atypia) as completely different endometrial diseases included in the same classification.
format	article
author	Maksim A. Sabantsev Svetlana V. Shramko Vladimir G. Levchenko Oleg A. Volkov Tatyana V. Tretyakova
author_facet	Maksim A. Sabantsev Svetlana V. Shramko Vladimir G. Levchenko Oleg A. Volkov Tatyana V. Tretyakova
author_sort	Maksim A. Sabantsev
title	Endometrial hyperplasia: without atypia and with atypia
title_short	Endometrial hyperplasia: without atypia and with atypia
title_full	Endometrial hyperplasia: without atypia and with atypia
title_fullStr	Endometrial hyperplasia: without atypia and with atypia
title_full_unstemmed	Endometrial hyperplasia: without atypia and with atypia
title_sort	endometrial hyperplasia: without atypia and with atypia
publisher	IP Berlin A.V.
publishDate	2021
url	https://doaj.org/article/5720f9cf9c2e46548e80c415663b46ec
work_keys_str_mv	AT maksimasabantsev endometrialhyperplasiawithoutatypiaandwithatypia AT svetlanavshramko endometrialhyperplasiawithoutatypiaandwithatypia AT vladimirglevchenko endometrialhyperplasiawithoutatypiaandwithatypia AT olegavolkov endometrialhyperplasiawithoutatypiaandwithatypia AT tatyanavtretyakova endometrialhyperplasiawithoutatypiaandwithatypia
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Endometrial hyperplasia: without atypia and with atypia

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