Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients
Julie Bertrand,1 Fabrice Caillol,1 Patrick Borentain,2 Jean-Luc Raoul,1 Laurent Heyries,2 Erwan Bories,1 Christian Pesenti,1 Jean-Philippe Ratone,2 Jean-Paul Bernard,2 René Gerolami,2 Marc Giovannini1 1Endoscopy Unit, Paoli Calmettes Institute, Marseille, France; 2Department of Hepato-Gas...
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Dove Medical Press
2015
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oai:doaj.org-article:57229c9e85a44a9f967fc243e55325272021-12-02T06:01:47ZPercutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients1179-1535https://doaj.org/article/57229c9e85a44a9f967fc243e55325272015-05-01T00:00:00Zhttp://www.dovepress.com/percutaneous-hepatic-radiofrequency-for-hepatocellular-carcinoma-resul-peer-reviewed-article-HMERhttps://doaj.org/toc/1179-1535Julie Bertrand,1 Fabrice Caillol,1 Patrick Borentain,2 Jean-Luc Raoul,1 Laurent Heyries,2 Erwan Bories,1 Christian Pesenti,1 Jean-Philippe Ratone,2 Jean-Paul Bernard,2 René Gerolami,2 Marc Giovannini1 1Endoscopy Unit, Paoli Calmettes Institute, Marseille, France; 2Department of Hepato-Gastroenterology, Conception Hospital, Marseille, France Abstract: Radiofrequency ablation (RFA) is a curative option for hepatocellular carcinoma (HCC), the most common primary malignancy of the liver. This bicentric retrospective study includes 46 patients admitted for their first percutaneous RFA for HCC. Sixty-three nodules were treated, with an average size of 32.5 mm. Our study confirms the efficiency of this technique for attaining necrosis of HCC nodules, with few complications. Subgroup studies according to RFA mode (mono- or multipolar), etiology of cirrhosis (alcoholic or viral), and HCC size showed better efficiency for multipolar RFA when applied to small tumors and better survival when the cirrhosis was due to viral infection. However, we noted a high rate of local recurrence in our and other recent works compared to previous studies, probably due to improved imaging techniques. The main problem is still de novo intrahepatic recurrence in diseased livers. Keywords: radiofrequency ablation, cirrhosis, HCCBertrJCaillol FBorentain PRaoul JLHeyries LBories EPesenti CRatone JPBernard JPGerolami RGiovannini MDove Medical PressarticleDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol 2015, Iss default, Pp 21-27 (2015) |
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Diseases of the digestive system. Gastroenterology RC799-869 |
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Diseases of the digestive system. Gastroenterology RC799-869 Bertr J Caillol F Borentain P Raoul JL Heyries L Bories E Pesenti C Ratone JP Bernard JP Gerolami R Giovannini M Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| description |
Julie Bertrand,1 Fabrice Caillol,1 Patrick Borentain,2 Jean-Luc Raoul,1 Laurent Heyries,2 Erwan Bories,1 Christian Pesenti,1 Jean-Philippe Ratone,2 Jean-Paul Bernard,2 René Gerolami,2 Marc Giovannini1 1Endoscopy Unit, Paoli Calmettes Institute, Marseille, France; 2Department of Hepato-Gastroenterology, Conception Hospital, Marseille, France Abstract: Radiofrequency ablation (RFA) is a curative option for hepatocellular carcinoma (HCC), the most common primary malignancy of the liver. This bicentric retrospective study includes 46 patients admitted for their first percutaneous RFA for HCC. Sixty-three nodules were treated, with an average size of 32.5 mm. Our study confirms the efficiency of this technique for attaining necrosis of HCC nodules, with few complications. Subgroup studies according to RFA mode (mono- or multipolar), etiology of cirrhosis (alcoholic or viral), and HCC size showed better efficiency for multipolar RFA when applied to small tumors and better survival when the cirrhosis was due to viral infection. However, we noted a high rate of local recurrence in our and other recent works compared to previous studies, probably due to improved imaging techniques. The main problem is still de novo intrahepatic recurrence in diseased livers. Keywords: radiofrequency ablation, cirrhosis, HCC |
| format |
article |
| author |
Bertr J Caillol F Borentain P Raoul JL Heyries L Bories E Pesenti C Ratone JP Bernard JP Gerolami R Giovannini M |
| author_facet |
Bertr J Caillol F Borentain P Raoul JL Heyries L Bories E Pesenti C Ratone JP Bernard JP Gerolami R Giovannini M |
| author_sort |
Bertr |
| title |
Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| title_short |
Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| title_full |
Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| title_fullStr |
Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| title_full_unstemmed |
Percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| title_sort |
percutaneous hepatic radiofrequency for hepatocellular carcinoma: results and outcome of 46 patients |
| publisher |
Dove Medical Press |
| publishDate |
2015 |
| url |
https://doaj.org/article/57229c9e85a44a9f967fc243e5532527 |
| work_keys_str_mv |
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1718400111149580288 |