Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>

Economic synthesis platforms for the production of animal vaccines could help reduce the overuse and misuse of antibiotics in animal husbandry, which contributes greatly to the increase of antibiotic resistance. Here, we describe a highly versatile, easy-to-use mix-and-match toolbox for the genera...

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Autores principales: Christa Litschko, Insa Budde, Monika Berger, Andrea Bethe, Julia Schulze, E. Alberto Alcala Orozco, Reza Mahour, Peter Goettig, Jana Indra Führing, Thomas Rexer, Rita Gerardy-Schahn, Mario Schubert, Timm Fiebig
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/5722c046760342c281fde9f8456cbd10
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spelling oai:doaj.org-article:5722c046760342c281fde9f8456cbd102021-11-03T21:15:03Z Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i> 2150-751110.1128/mBio.00897-21https://doaj.org/article/5722c046760342c281fde9f8456cbd102021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00897-21https://doaj.org/toc/2150-7511 Economic synthesis platforms for the production of animal vaccines could help reduce the overuse and misuse of antibiotics in animal husbandry, which contributes greatly to the increase of antibiotic resistance. Here, we describe a highly versatile, easy-to-use mix-and-match toolbox for the generation of glycerol-phosphate-containing capsule polymers that can serve as antigens in glycoconjugate vaccines against Actinobacillus pleuropneumoniaeBibersteinia trehalosiChrista LitschkoInsa BuddeMonika BergerAndrea BetheJulia SchulzeE. Alberto Alcala OrozcoReza MahourPeter GoettigJana Indra FühringThomas RexerRita Gerardy-SchahnMario SchubertTimm FiebigAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Christa Litschko
Insa Budde
Monika Berger
Andrea Bethe
Julia Schulze
E. Alberto Alcala Orozco
Reza Mahour
Peter Goettig
Jana Indra Führing
Thomas Rexer
Rita Gerardy-Schahn
Mario Schubert
Timm Fiebig
Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
description Economic synthesis platforms for the production of animal vaccines could help reduce the overuse and misuse of antibiotics in animal husbandry, which contributes greatly to the increase of antibiotic resistance. Here, we describe a highly versatile, easy-to-use mix-and-match toolbox for the generation of glycerol-phosphate-containing capsule polymers that can serve as antigens in glycoconjugate vaccines against Actinobacillus pleuropneumoniaeBibersteinia trehalosi
format article
author Christa Litschko
Insa Budde
Monika Berger
Andrea Bethe
Julia Schulze
E. Alberto Alcala Orozco
Reza Mahour
Peter Goettig
Jana Indra Führing
Thomas Rexer
Rita Gerardy-Schahn
Mario Schubert
Timm Fiebig
author_facet Christa Litschko
Insa Budde
Monika Berger
Andrea Bethe
Julia Schulze
E. Alberto Alcala Orozco
Reza Mahour
Peter Goettig
Jana Indra Führing
Thomas Rexer
Rita Gerardy-Schahn
Mario Schubert
Timm Fiebig
author_sort Christa Litschko
title Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
title_short Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
title_full Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
title_fullStr Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
title_full_unstemmed Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from <i>Actinobacillus pleuropneumoniae</i> , <i>Neisseria meningitidis</i> , and <i>Bibersteinia trehalosi</i>
title_sort mix-and-match system for the enzymatic synthesis of enantiopure glycerol-3-phosphate-containing capsule polymer backbones from <i>actinobacillus pleuropneumoniae</i> , <i>neisseria meningitidis</i> , and <i>bibersteinia trehalosi</i>
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/5722c046760342c281fde9f8456cbd10
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