EGF Receptor Transactivation by Endothelin-1 Increased CHSY-1 Mediated by NADPH Oxidase and Phosphorylation of ERK1/2

Objective: Growth factors [transforming growth factor-β (TGF-β), epidermal growth factor (EGF), endothelin-1 (ET-1)] stimulate proteoglycan synthesis resulting in retention and accumulation of low density lipoprotein (LDL) in vessel intima and leading to atherosclerosis development. This study inves...

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Bibliographic Details
Main Authors: Hossein Babaahmadi-Rezaei, Alireza Kheirollah, Mojtaba Rashidi, Faezeh Seif, Zahra Niknam, Masoumeh Zamanpour
Format: article
Language:EN
Published: Royan Institute (ACECR), Tehran 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/572497b1833d43bf9a026bca93e31231
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