EGF Receptor Transactivation by Endothelin-1 Increased CHSY-1 Mediated by NADPH Oxidase and Phosphorylation of ERK1/2
Objective: Growth factors [transforming growth factor-β (TGF-β), epidermal growth factor (EGF), endothelin-1 (ET-1)] stimulate proteoglycan synthesis resulting in retention and accumulation of low density lipoprotein (LDL) in vessel intima and leading to atherosclerosis development. This study inves...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
Royan Institute (ACECR), Tehran
2021
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Subjects: | |
Online Access: | https://doaj.org/article/572497b1833d43bf9a026bca93e31231 |
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