Effects of activation of the LINE-1 antisense promoter on the growth of cultured cells

Abstract Long interspersed element 1 (LINE-1, or L1) is a retrotransposon that constitutes ~ 17% of the human genome. Although ~ 6000 full-length L1s spread throughout the human genome, their biological significance remains undetermined. The L1 5′ untranslated region has bidirectional promoter activ...

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Autores principales: Tomoyuki Honda, Yuki Nishikawa, Kensuke Nishimura, Da Teng, Keiko Takemoto, Keiji Ueda
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5730b6c9b18f44d38e3616378b09098a
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