Inhibition of human neutrophil elastase by pentacyclic triterpenes.

Inhibition of human neutrophil elastase by pentacyclic triterpenes.

<h4>Scope</h4>Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat, the only clinically registered synthesized HNE inhibitor, is largely limited by its risk of organ toxic...

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Autores principales: Li Feng, Xiaoyu Liu, Weiliang Zhu, Fujiang Guo, Yingchun Wu, Rui Wang, Kaixian Chen, Cheng Huang, Yiming Li
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/5736b69e0d9444e785eebe67e0396048
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