The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.

The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.

<h4>Background and aims</h4>A polymorphism in adiponutrin/patatin-like phospholipase-3 gene (PNPLA3), rs738409 C->G, encoding for the I148M variant, is the strongest genetic determinant of liver fat and ALT levels in adulthood and childhood obesity. Aims of this study were i) to analy...

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Autores principales: Emanuele Miraglia del Giudice, Anna Grandone, Grazia Cirillo, Nicola Santoro, Alessandra Amato, Carmine Brienza, Piera Savarese, Pierluigi Marzuillo, Laura Perrone
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/57375d409ca54adb9abdbe4642d68610
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