The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.
<h4>Background and aims</h4>A polymorphism in adiponutrin/patatin-like phospholipase-3 gene (PNPLA3), rs738409 C->G, encoding for the I148M variant, is the strongest genetic determinant of liver fat and ALT levels in adulthood and childhood obesity. Aims of this study were i) to analy...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/57375d409ca54adb9abdbe4642d68610 |
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