A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium
Auxotrophic bacteria rely on transporters to acquire essential compounds from their environment. Here, Hernandez-Valdes et al. show that a riboswitch generates long-term, stable heterogenous expression of a high-affinity methionine transporter in auxotrophic Lactococcus lactis.
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Nature Portfolio
2020
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oai:doaj.org-article:573b578017b54354aca3d2f3ce1c27a02021-12-02T14:41:25ZA riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium10.1038/s41467-020-15017-12041-1723https://doaj.org/article/573b578017b54354aca3d2f3ce1c27a02020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15017-1https://doaj.org/toc/2041-1723Auxotrophic bacteria rely on transporters to acquire essential compounds from their environment. Here, Hernandez-Valdes et al. show that a riboswitch generates long-term, stable heterogenous expression of a high-affinity methionine transporter in auxotrophic Lactococcus lactis.Jhonatan A. Hernandez-ValdesJordi van GestelOscar P. KuipersNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Jhonatan A. Hernandez-Valdes Jordi van Gestel Oscar P. Kuipers A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
description |
Auxotrophic bacteria rely on transporters to acquire essential compounds from their environment. Here, Hernandez-Valdes et al. show that a riboswitch generates long-term, stable heterogenous expression of a high-affinity methionine transporter in auxotrophic Lactococcus lactis. |
format |
article |
author |
Jhonatan A. Hernandez-Valdes Jordi van Gestel Oscar P. Kuipers |
author_facet |
Jhonatan A. Hernandez-Valdes Jordi van Gestel Oscar P. Kuipers |
author_sort |
Jhonatan A. Hernandez-Valdes |
title |
A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
title_short |
A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
title_full |
A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
title_fullStr |
A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
title_full_unstemmed |
A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
title_sort |
riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/573b578017b54354aca3d2f3ce1c27a0 |
work_keys_str_mv |
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