IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

Membrane contact sites between the ER and mitochondria are known to convey calcium signals between these two organelles via IP3 receptors, but the molecular mechanisms are currently unclear. Here, the authors show that IP3 receptors play a structural tethering role in maintaining ER-mitochondrial co...

Full description

Saved in:
Bibliographic Details
Main Authors: Adam Bartok, David Weaver, Tünde Golenár, Zuzana Nichtova, Máté Katona, Száva Bánsághi, Kamil J. Alzayady, V. Kaye Thomas, Hideaki Ando, Katsuhiko Mikoshiba, Suresh K. Joseph, David I. Yule, György Csordás, György Hajnóczky
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
Q
Online Access:https://doaj.org/article/573c9a6e3c934f97817996bbe29c011b
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/573c9a6e3c934f97817996bbe29c011b

Similar Items