GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.
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Nature Portfolio
2021
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oai:doaj.org-article:5741b558f57c49e99ab8db7f468bfa022021-12-02T10:52:47ZGWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression10.1038/s41467-021-21280-72041-1723https://doaj.org/article/5741b558f57c49e99ab8db7f468bfa022021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21280-7https://doaj.org/toc/2041-1723Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.Yeda WuGraham K. MurrayEnda M. ByrneJulia SidorenkoPeter M. VisscherNaomi R. WrayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
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Science Q Yeda Wu Graham K. Murray Enda M. Byrne Julia Sidorenko Peter M. Visscher Naomi R. Wray GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression |
description |
Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression. |
format |
article |
author |
Yeda Wu Graham K. Murray Enda M. Byrne Julia Sidorenko Peter M. Visscher Naomi R. Wray |
author_facet |
Yeda Wu Graham K. Murray Enda M. Byrne Julia Sidorenko Peter M. Visscher Naomi R. Wray |
author_sort |
Yeda Wu |
title |
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression |
title_short |
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression |
title_full |
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression |
title_fullStr |
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression |
title_full_unstemmed |
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression |
title_sort |
gwas of peptic ulcer disease implicates helicobacter pylori infection, other gastrointestinal disorders and depression |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5741b558f57c49e99ab8db7f468bfa02 |
work_keys_str_mv |
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