GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.

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Autores principales: Yeda Wu, Graham K. Murray, Enda M. Byrne, Julia Sidorenko, Peter M. Visscher, Naomi R. Wray
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5741b558f57c49e99ab8db7f468bfa02
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spelling oai:doaj.org-article:5741b558f57c49e99ab8db7f468bfa022021-12-02T10:52:47ZGWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression10.1038/s41467-021-21280-72041-1723https://doaj.org/article/5741b558f57c49e99ab8db7f468bfa022021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21280-7https://doaj.org/toc/2041-1723Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.Yeda WuGraham K. MurrayEnda M. ByrneJulia SidorenkoPeter M. VisscherNaomi R. WrayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yeda Wu
Graham K. Murray
Enda M. Byrne
Julia Sidorenko
Peter M. Visscher
Naomi R. Wray
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
description Genetic factors contribute to peptic ulcer disease (PUD). Here, the authors perform a genome-wide association analysis on PUD in the UK Biobank, highlighting shared architecture with other gastrointestinal disorders and possible causal links with depression.
format article
author Yeda Wu
Graham K. Murray
Enda M. Byrne
Julia Sidorenko
Peter M. Visscher
Naomi R. Wray
author_facet Yeda Wu
Graham K. Murray
Enda M. Byrne
Julia Sidorenko
Peter M. Visscher
Naomi R. Wray
author_sort Yeda Wu
title GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
title_short GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
title_full GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
title_fullStr GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
title_full_unstemmed GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
title_sort gwas of peptic ulcer disease implicates helicobacter pylori infection, other gastrointestinal disorders and depression
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5741b558f57c49e99ab8db7f468bfa02
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