Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)

Objective: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this resea...

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Autor principal:	Muhammad Fadhol Romdhoni
Formato:	article
Lenguaje:	EN ID
Publicado:	Universitas Muhammadiyah Semarang 2016
Materias:	gastritis formaldehyde stomach mucosal rat Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/5748fdbd92c147da836ec55b71a2376c
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spelling	oai:doaj.org-article:5748fdbd92c147da836ec55b71a2376c2021-11-10T03:15:17ZPengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)2407-05052774-231810.26714/magnamed.1.2.2015.162-169https://doaj.org/article/5748fdbd92c147da836ec55b71a2376c2016-05-01T00:00:00Zhttps://jurnal.unimus.ac.id/index.php/APKKM/article/view/1933https://doaj.org/toc/2407-0505https://doaj.org/toc/2774-2318Objective: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this research is prove the Effect of Formaldehyde peroral subacute on the stomach mucosal of White Rat Strain Wistar (Rattus Norvegicus strain wistar)Method & Materials: The design of the study was pure experimental which usingThe Posttest Control Group Design. Sample were white mice which divided into 4 groups. Group I is as a control, without formaldehyde, and another groups were given with formaldehyde doses 20 ppm, 40 ppm, and 80 ppm. Result and discussion: The results should that formaldehyde can cause hyperplasia, hypertrophic, atopic, chafe (ANOVA p=0.000). The mechanism of action possibility as DNA cross-linked by protein than gene expression anormal.Conclusions: The study concluded that formaldehyde can cause hyperplasia, hypertrophic, atopic, and chafe on the mucosal stomach of white rat strain wistar and further study was needed to know minimum doses than can change of stomach mucosal and than mecahanism of action about them.Muhammad Fadhol RomdhoniUniversitas Muhammadiyah Semarangarticlegastritisformaldehydestomach mucosalratMedicine (General)R5-920ENIDMagna Medika, Vol 1, Iss 2, Pp 162-169 (2016)
institution	DOAJ
collection	DOAJ
language	EN ID
topic	gastritis formaldehyde stomach mucosal rat Medicine (General) R5-920
spellingShingle	gastritis formaldehyde stomach mucosal rat Medicine (General) R5-920 Muhammad Fadhol Romdhoni Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
description	Objective: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this research is prove the Effect of Formaldehyde peroral subacute on the stomach mucosal of White Rat Strain Wistar (Rattus Norvegicus strain wistar)Method & Materials: The design of the study was pure experimental which usingThe Posttest Control Group Design. Sample were white mice which divided into 4 groups. Group I is as a control, without formaldehyde, and another groups were given with formaldehyde doses 20 ppm, 40 ppm, and 80 ppm. Result and discussion: The results should that formaldehyde can cause hyperplasia, hypertrophic, atopic, chafe (ANOVA p=0.000). The mechanism of action possibility as DNA cross-linked by protein than gene expression anormal.Conclusions: The study concluded that formaldehyde can cause hyperplasia, hypertrophic, atopic, and chafe on the mucosal stomach of white rat strain wistar and further study was needed to know minimum doses than can change of stomach mucosal and than mecahanism of action about them.
format	article
author	Muhammad Fadhol Romdhoni
author_facet	Muhammad Fadhol Romdhoni
author_sort	Muhammad Fadhol Romdhoni
title	Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
title_short	Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
title_full	Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
title_fullStr	Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
title_full_unstemmed	Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
title_sort	pengaruh pemberian formalin peroral terhadap mukosa lambung tikus putih strain wistar (rattus norvegicus strain wistar)
publisher	Universitas Muhammadiyah Semarang
publishDate	2016
url	https://doaj.org/article/5748fdbd92c147da836ec55b71a2376c
work_keys_str_mv	AT muhammadfadholromdhoni pengaruhpemberianformalinperoralterhadapmukosalambungtikusputihstrainwistarrattusnorvegicusstrainwistar
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Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)

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