Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion

In addition to regulating programmed cell death, caspases also have non-apoptotic roles. Here, the authors show that low level caspase activity prevents cell migration to maintain tissue integrity.

Guardado en:

Detalles Bibliográficos
Autores principales:	Anna Gorelick-Ashkenazi, Ron Weiss, Lena Sapozhnikov, Anat Florentin, Lama Tarayrah-Ibraheim, Dima Dweik, Keren Yacobi-Sharon, Eli Arama
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/575825199d39457e9c2e5afd24d2d7eb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:575825199d39457e9c2e5afd24d2d7eb
record_format	dspace
spelling	oai:doaj.org-article:575825199d39457e9c2e5afd24d2d7eb2021-12-02T14:40:02ZCaspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion10.1038/s41467-018-05204-62041-1723https://doaj.org/article/575825199d39457e9c2e5afd24d2d7eb2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05204-6https://doaj.org/toc/2041-1723In addition to regulating programmed cell death, caspases also have non-apoptotic roles. Here, the authors show that low level caspase activity prevents cell migration to maintain tissue integrity.Anna Gorelick-AshkenaziRon WeissLena SapozhnikovAnat FlorentinLama Tarayrah-IbraheimDima DweikKeren Yacobi-SharonEli AramaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna Gorelick-Ashkenazi Ron Weiss Lena Sapozhnikov Anat Florentin Lama Tarayrah-Ibraheim Dima Dweik Keren Yacobi-Sharon Eli Arama Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
description	In addition to regulating programmed cell death, caspases also have non-apoptotic roles. Here, the authors show that low level caspase activity prevents cell migration to maintain tissue integrity.
format	article
author	Anna Gorelick-Ashkenazi Ron Weiss Lena Sapozhnikov Anat Florentin Lama Tarayrah-Ibraheim Dima Dweik Keren Yacobi-Sharon Eli Arama
author_facet	Anna Gorelick-Ashkenazi Ron Weiss Lena Sapozhnikov Anat Florentin Lama Tarayrah-Ibraheim Dima Dweik Keren Yacobi-Sharon Eli Arama
author_sort	Anna Gorelick-Ashkenazi
title	Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
title_short	Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
title_full	Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
title_fullStr	Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
title_full_unstemmed	Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
title_sort	caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/575825199d39457e9c2e5afd24d2d7eb
work_keys_str_mv	AT annagorelickashkenazi caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT ronweiss caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT lenasapozhnikov caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT anatflorentin caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT lamatarayrahibraheim caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT dimadweik caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT kerenyacobisharon caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion AT eliarama caspasesmaintaintissueintegritybyanapoptosisindependentinhibitionofcellmigrationandinvasion
_version_	1718390414620229632

Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion

Ejemplares similares