The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17 CD4 T cells.

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Autores principales: Danielle Minns, Katie J. Smith, Virginia Alessandrini, Gareth Hardisty, Lauren Melrose, Lucy Jackson-Jones, Andrew S. MacDonald, Donald J. Davidson, Emily Gwyer Findlay
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/575b66e7e8b04cad96678a2c55c7e867
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spelling oai:doaj.org-article:575b66e7e8b04cad96678a2c55c7e8672021-12-02T13:34:29ZThe neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation10.1038/s41467-021-21533-52041-1723https://doaj.org/article/575b66e7e8b04cad96678a2c55c7e8672021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21533-5https://doaj.org/toc/2041-1723Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17 CD4 T cells.Danielle MinnsKatie J. SmithVirginia AlessandriniGareth HardistyLauren MelroseLucy Jackson-JonesAndrew S. MacDonaldDonald J. DavidsonEmily Gwyer FindlayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Danielle Minns
Katie J. Smith
Virginia Alessandrini
Gareth Hardisty
Lauren Melrose
Lucy Jackson-Jones
Andrew S. MacDonald
Donald J. Davidson
Emily Gwyer Findlay
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
description Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17 CD4 T cells.
format article
author Danielle Minns
Katie J. Smith
Virginia Alessandrini
Gareth Hardisty
Lauren Melrose
Lucy Jackson-Jones
Andrew S. MacDonald
Donald J. Davidson
Emily Gwyer Findlay
author_facet Danielle Minns
Katie J. Smith
Virginia Alessandrini
Gareth Hardisty
Lauren Melrose
Lucy Jackson-Jones
Andrew S. MacDonald
Donald J. Davidson
Emily Gwyer Findlay
author_sort Danielle Minns
title The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
title_short The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
title_full The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
title_fullStr The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
title_full_unstemmed The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
title_sort neutrophil antimicrobial peptide cathelicidin promotes th17 differentiation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/575b66e7e8b04cad96678a2c55c7e867
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