The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17 CD4 T cells.
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Nature Portfolio
2021
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oai:doaj.org-article:575b66e7e8b04cad96678a2c55c7e8672021-12-02T13:34:29ZThe neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation10.1038/s41467-021-21533-52041-1723https://doaj.org/article/575b66e7e8b04cad96678a2c55c7e8672021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21533-5https://doaj.org/toc/2041-1723Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17 CD4 T cells.Danielle MinnsKatie J. SmithVirginia AlessandriniGareth HardistyLauren MelroseLucy Jackson-JonesAndrew S. MacDonaldDonald J. DavidsonEmily Gwyer FindlayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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Science Q Danielle Minns Katie J. Smith Virginia Alessandrini Gareth Hardisty Lauren Melrose Lucy Jackson-Jones Andrew S. MacDonald Donald J. Davidson Emily Gwyer Findlay The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation |
description |
Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17 CD4 T cells. |
format |
article |
author |
Danielle Minns Katie J. Smith Virginia Alessandrini Gareth Hardisty Lauren Melrose Lucy Jackson-Jones Andrew S. MacDonald Donald J. Davidson Emily Gwyer Findlay |
author_facet |
Danielle Minns Katie J. Smith Virginia Alessandrini Gareth Hardisty Lauren Melrose Lucy Jackson-Jones Andrew S. MacDonald Donald J. Davidson Emily Gwyer Findlay |
author_sort |
Danielle Minns |
title |
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation |
title_short |
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation |
title_full |
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation |
title_fullStr |
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation |
title_full_unstemmed |
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation |
title_sort |
neutrophil antimicrobial peptide cathelicidin promotes th17 differentiation |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/575b66e7e8b04cad96678a2c55c7e867 |
work_keys_str_mv |
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