Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates
Some bacterial lineages appear to be pre-disposed to evolving antibiotic resistance. Here, the authors show that differential expression of an efflux pump causes widespread variation in evolvability across Staphylococcus aureus isolates, and chemical inhibition of the pump prevents resistance evolut...
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| Auteurs principaux: | Andrei Papkou, Jessica Hedge, Natalia Kapel, Bernadette Young, R. Craig MacLean |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/57622c4011834f13aa48b1b348252284 |
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