Adaptive laboratory evolution of a genome-reduced Escherichia coli
Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism.
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Nature Portfolio
2019
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oai:doaj.org-article:5767dc044b0944219925d7b9428faa082021-12-02T16:58:14ZAdaptive laboratory evolution of a genome-reduced Escherichia coli10.1038/s41467-019-08888-62041-1723https://doaj.org/article/5767dc044b0944219925d7b9428faa082019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08888-6https://doaj.org/toc/2041-1723Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism.Donghui ChoeJun Hyoung LeeMinseob YooSoonkyu HwangBong Hyun SungSuhyung ChoBernhard PalssonSun Chang KimByung-Kwan ChoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Donghui Choe Jun Hyoung Lee Minseob Yoo Soonkyu Hwang Bong Hyun Sung Suhyung Cho Bernhard Palsson Sun Chang Kim Byung-Kwan Cho Adaptive laboratory evolution of a genome-reduced Escherichia coli |
description |
Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism. |
format |
article |
author |
Donghui Choe Jun Hyoung Lee Minseob Yoo Soonkyu Hwang Bong Hyun Sung Suhyung Cho Bernhard Palsson Sun Chang Kim Byung-Kwan Cho |
author_facet |
Donghui Choe Jun Hyoung Lee Minseob Yoo Soonkyu Hwang Bong Hyun Sung Suhyung Cho Bernhard Palsson Sun Chang Kim Byung-Kwan Cho |
author_sort |
Donghui Choe |
title |
Adaptive laboratory evolution of a genome-reduced Escherichia coli |
title_short |
Adaptive laboratory evolution of a genome-reduced Escherichia coli |
title_full |
Adaptive laboratory evolution of a genome-reduced Escherichia coli |
title_fullStr |
Adaptive laboratory evolution of a genome-reduced Escherichia coli |
title_full_unstemmed |
Adaptive laboratory evolution of a genome-reduced Escherichia coli |
title_sort |
adaptive laboratory evolution of a genome-reduced escherichia coli |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/5767dc044b0944219925d7b9428faa08 |
work_keys_str_mv |
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1718382327839588352 |