Natriuretic Peptides in Chronic Heart Failure
Normal brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels are helpful in excluding chronic heart failure in the ambulatory setting, although they have been studied less well and possibly less accurately than in acute care. They may also be of help in screening patients at risk...
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Radcliffe Medical Media
2019
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oai:doaj.org-article:57768560db9c46f5a594691b34c910ef2021-12-04T16:00:49ZNatriuretic Peptides in Chronic Heart Failure10.15420/cfr.2018.26.12057-75592057-7540https://doaj.org/article/57768560db9c46f5a594691b34c910ef2019-01-01T00:00:00Zhttps://www.cfrjournal.com/articles/natriuretic-peptides-chronic-heart-failurehttps://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Normal brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels are helpful in excluding chronic heart failure in the ambulatory setting, although they have been studied less well and possibly less accurately than in acute care. They may also be of help in screening patients at risk to intervene and reduce the development of heart failure. Natriuretic peptides are also excellent prognostic markers of chronic heart failure, but the clinical value of such prognostic information is less clear. One possible application for this information is guiding medical therapy in chronic heart failure. Many studies have investigated this approach, but results are mixed and do not clearly show improvement in outcome. Still, it may be that in patients with reduced ejection fraction and few comorbidities, measuring NT-proBNP to uptitrate medication improves prognosis.Hans-Peter Brunner-La RoccaSandra Sanders-van WijkRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 5, Iss 1, Pp 44-49 (2019) |
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Diseases of the circulatory (Cardiovascular) system RC666-701 |
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Diseases of the circulatory (Cardiovascular) system RC666-701 Hans-Peter Brunner-La Rocca Sandra Sanders-van Wijk Natriuretic Peptides in Chronic Heart Failure |
description |
Normal brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels are helpful in excluding chronic heart failure in the ambulatory setting, although they have been studied less well and possibly less accurately than in acute care. They may also be of help in screening patients at risk to intervene and reduce the development of heart failure. Natriuretic peptides are also excellent prognostic markers of chronic heart failure, but the clinical value of such prognostic information is less clear. One possible application for this information is guiding medical therapy in chronic heart failure. Many studies have investigated this approach, but results are mixed and do not clearly show improvement in outcome. Still, it may be that in patients with reduced ejection fraction and few comorbidities, measuring NT-proBNP to uptitrate medication improves prognosis. |
format |
article |
author |
Hans-Peter Brunner-La Rocca Sandra Sanders-van Wijk |
author_facet |
Hans-Peter Brunner-La Rocca Sandra Sanders-van Wijk |
author_sort |
Hans-Peter Brunner-La Rocca |
title |
Natriuretic Peptides in Chronic Heart Failure |
title_short |
Natriuretic Peptides in Chronic Heart Failure |
title_full |
Natriuretic Peptides in Chronic Heart Failure |
title_fullStr |
Natriuretic Peptides in Chronic Heart Failure |
title_full_unstemmed |
Natriuretic Peptides in Chronic Heart Failure |
title_sort |
natriuretic peptides in chronic heart failure |
publisher |
Radcliffe Medical Media |
publishDate |
2019 |
url |
https://doaj.org/article/57768560db9c46f5a594691b34c910ef |
work_keys_str_mv |
AT hanspeterbrunnerlarocca natriureticpeptidesinchronicheartfailure AT sandrasandersvanwijk natriureticpeptidesinchronicheartfailure |
_version_ |
1718372795161772032 |