Landscape of transcriptomic interactions between breast cancer and its microenvironment

The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.

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Detalles Bibliográficos
Autores principales: Natalie S. Fox, Syed Haider, Adrian L. Harris, Paul C. Boutros
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/57800ebd8fd4435086e9bf0b582732f5
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Sumario:The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.