Landscape of transcriptomic interactions between breast cancer and its microenvironment

The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.

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Autores principales: Natalie S. Fox, Syed Haider, Adrian L. Harris, Paul C. Boutros
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/57800ebd8fd4435086e9bf0b582732f5
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spelling oai:doaj.org-article:57800ebd8fd4435086e9bf0b582732f52021-12-02T14:39:56ZLandscape of transcriptomic interactions between breast cancer and its microenvironment10.1038/s41467-019-10929-z2041-1723https://doaj.org/article/57800ebd8fd4435086e9bf0b582732f52019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10929-zhttps://doaj.org/toc/2041-1723The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.Natalie S. FoxSyed HaiderAdrian L. HarrisPaul C. BoutrosNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Natalie S. Fox
Syed Haider
Adrian L. Harris
Paul C. Boutros
Landscape of transcriptomic interactions between breast cancer and its microenvironment
description The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.
format article
author Natalie S. Fox
Syed Haider
Adrian L. Harris
Paul C. Boutros
author_facet Natalie S. Fox
Syed Haider
Adrian L. Harris
Paul C. Boutros
author_sort Natalie S. Fox
title Landscape of transcriptomic interactions between breast cancer and its microenvironment
title_short Landscape of transcriptomic interactions between breast cancer and its microenvironment
title_full Landscape of transcriptomic interactions between breast cancer and its microenvironment
title_fullStr Landscape of transcriptomic interactions between breast cancer and its microenvironment
title_full_unstemmed Landscape of transcriptomic interactions between breast cancer and its microenvironment
title_sort landscape of transcriptomic interactions between breast cancer and its microenvironment
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/57800ebd8fd4435086e9bf0b582732f5
work_keys_str_mv AT nataliesfox landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment
AT syedhaider landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment
AT adrianlharris landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment
AT paulcboutros landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment
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