Landscape of transcriptomic interactions between breast cancer and its microenvironment
The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.
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Nature Portfolio
2019
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oai:doaj.org-article:57800ebd8fd4435086e9bf0b582732f52021-12-02T14:39:56ZLandscape of transcriptomic interactions between breast cancer and its microenvironment10.1038/s41467-019-10929-z2041-1723https://doaj.org/article/57800ebd8fd4435086e9bf0b582732f52019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10929-zhttps://doaj.org/toc/2041-1723The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.Natalie S. FoxSyed HaiderAdrian L. HarrisPaul C. BoutrosNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Natalie S. Fox Syed Haider Adrian L. Harris Paul C. Boutros Landscape of transcriptomic interactions between breast cancer and its microenvironment |
description |
The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information. |
format |
article |
author |
Natalie S. Fox Syed Haider Adrian L. Harris Paul C. Boutros |
author_facet |
Natalie S. Fox Syed Haider Adrian L. Harris Paul C. Boutros |
author_sort |
Natalie S. Fox |
title |
Landscape of transcriptomic interactions between breast cancer and its microenvironment |
title_short |
Landscape of transcriptomic interactions between breast cancer and its microenvironment |
title_full |
Landscape of transcriptomic interactions between breast cancer and its microenvironment |
title_fullStr |
Landscape of transcriptomic interactions between breast cancer and its microenvironment |
title_full_unstemmed |
Landscape of transcriptomic interactions between breast cancer and its microenvironment |
title_sort |
landscape of transcriptomic interactions between breast cancer and its microenvironment |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/57800ebd8fd4435086e9bf0b582732f5 |
work_keys_str_mv |
AT nataliesfox landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment AT syedhaider landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment AT adrianlharris landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment AT paulcboutros landscapeoftranscriptomicinteractionsbetweenbreastcanceranditsmicroenvironment |
_version_ |
1718390472920006656 |