Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia

Zi Di Lim, 1, 2 Kok Tian Oo, 1, 2 Evelyn Li Min Tai, 1, 2 Ismail Shatriah 1, 2 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; 2Ophthalmology Clinic, Hospital Universiti Usains Malaysia, Kubang Kerian 16150, Kelantan, Ma...

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Autores principales:	Lim ZD, Oo KT, Tai ELM, Shatriah I
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	winrop retinopathy of prematurity sensitivity specificity Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/5780d30bcf64412588055709cd107e0e
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spelling	oai:doaj.org-article:5780d30bcf64412588055709cd107e0e2021-12-02T09:14:56ZEfficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia1177-5483https://doaj.org/article/5780d30bcf64412588055709cd107e0e2020-04-01T00:00:00Zhttps://www.dovepress.com/efficacy-of-winrop-as-a-screening-tool-for-retinopathy-of-prematurity--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Zi Di Lim, 1, 2 Kok Tian Oo, 1, 2 Evelyn Li Min Tai, 1, 2 Ismail Shatriah 1, 2 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; 2Ophthalmology Clinic, Hospital Universiti Usains Malaysia, Kubang Kerian 16150, Kelantan, MalaysiaCorrespondence: Ismail ShatriahDepartment of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, MalaysiaEmail shatriah@usm.myPurpose: To evaluate the efficacy of the “weight, insulin-like growth factor 1, neonatal retinopathy of prematurity” (WINROP) algorithm in predicting retinopathy of prematurity (ROP) requiring treatment in Malaysia.Participants: This was a retrospective study involving premature infants with gestational age less than 32 weeks treated from September 2016 to March 2019 in Hospital Universiti Sains Malaysia. Clinical diagnosis was made based on Early Treatment Retinopathy of Prematurity study. Participants’ weekly weight gain since birth was entered in the website (http://winrop.com), along with date of birth, gestational age and final clinical examination outcome. WINROP software signals an alarm if an infant is at high risk of developing ROP requiring treatment during weight data entry. By using the alarm status, the sensitivity and specificity of this algorithm for predicting ROP requiring treatment were obtained.Results: Ninety-two infants were included in this study. An alarm was detected in 67 infants (72.8%). There were a total of 53 infants (54.6%) with no ROP, 15 (16.3%) of whom developed stage 1 ROP, 10 (10.8%) who developed stage 2 ROP and 14 infants (15.2%) who developed stage 3 ROP. In our study, WINROP sensitivity was 95.2% and specificity was 33.8%.Conclusion: WINROP is recommended as an initial screening tool for premature infants at risk of developing treatment-requiring ROP in Malaysia. It may help to alert clinicians managing severely ill infants when clinical examinations are less possible.Keywords: WINROP, retinopathy of prematurity, sensitivity, specificityLim ZDOo KTTai ELMShatriah IDove Medical Pressarticlewinropretinopathy of prematuritysensitivityspecificityOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 1101-1106 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	winrop retinopathy of prematurity sensitivity specificity Ophthalmology RE1-994
spellingShingle	winrop retinopathy of prematurity sensitivity specificity Ophthalmology RE1-994 Lim ZD Oo KT Tai ELM Shatriah I Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia
description	Zi Di Lim, 1, 2 Kok Tian Oo, 1, 2 Evelyn Li Min Tai, 1, 2 Ismail Shatriah 1, 2 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; 2Ophthalmology Clinic, Hospital Universiti Usains Malaysia, Kubang Kerian 16150, Kelantan, MalaysiaCorrespondence: Ismail ShatriahDepartment of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, MalaysiaEmail shatriah@usm.myPurpose: To evaluate the efficacy of the “weight, insulin-like growth factor 1, neonatal retinopathy of prematurity” (WINROP) algorithm in predicting retinopathy of prematurity (ROP) requiring treatment in Malaysia.Participants: This was a retrospective study involving premature infants with gestational age less than 32 weeks treated from September 2016 to March 2019 in Hospital Universiti Sains Malaysia. Clinical diagnosis was made based on Early Treatment Retinopathy of Prematurity study. Participants’ weekly weight gain since birth was entered in the website (http://winrop.com), along with date of birth, gestational age and final clinical examination outcome. WINROP software signals an alarm if an infant is at high risk of developing ROP requiring treatment during weight data entry. By using the alarm status, the sensitivity and specificity of this algorithm for predicting ROP requiring treatment were obtained.Results: Ninety-two infants were included in this study. An alarm was detected in 67 infants (72.8%). There were a total of 53 infants (54.6%) with no ROP, 15 (16.3%) of whom developed stage 1 ROP, 10 (10.8%) who developed stage 2 ROP and 14 infants (15.2%) who developed stage 3 ROP. In our study, WINROP sensitivity was 95.2% and specificity was 33.8%.Conclusion: WINROP is recommended as an initial screening tool for premature infants at risk of developing treatment-requiring ROP in Malaysia. It may help to alert clinicians managing severely ill infants when clinical examinations are less possible.Keywords: WINROP, retinopathy of prematurity, sensitivity, specificity
format	article
author	Lim ZD Oo KT Tai ELM Shatriah I
author_facet	Lim ZD Oo KT Tai ELM Shatriah I
author_sort	Lim ZD
title	Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia
title_short	Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia
title_full	Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia
title_fullStr	Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia
title_full_unstemmed	Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia
title_sort	efficacy of winrop as a screening tool for retinopathy of prematurity in the east coast of malaysia
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/5780d30bcf64412588055709cd107e0e
work_keys_str_mv	AT limzd efficacyofwinropasascreeningtoolforretinopathyofprematurityintheeastcoastofmalaysia AT ookt efficacyofwinropasascreeningtoolforretinopathyofprematurityintheeastcoastofmalaysia AT taielm efficacyofwinropasascreeningtoolforretinopathyofprematurityintheeastcoastofmalaysia AT shatriahi efficacyofwinropasascreeningtoolforretinopathyofprematurityintheeastcoastofmalaysia
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Efficacy of WINROP as a Screening Tool for Retinopathy of Prematurity in the East Coast of Malaysia

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