SUMO targets the APC/C to regulate transition from metaphase to anaphase

Signal transduction by small ubiquitin-like modifier (SUMO) is important for cell cycle progression. Here the authors show that SUMOylation regulates the APC/C complex, a master orchestrator of metaphase to anaphase transition, with consequences for mitotic progression.

Guardado en:

Detalles Bibliográficos
Autores principales:	Karolin Eifler, Sabine A. G. Cuijpers, Edwin Willemstein, Jonne A. Raaijmakers, Dris El Atmioui, Huib Ovaa, René H. Medema, Alfred C. O. Vertegaal
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5797f95b8c1741f1b90f2f7c055ba779
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5797f95b8c1741f1b90f2f7c055ba779
record_format	dspace
spelling	oai:doaj.org-article:5797f95b8c1741f1b90f2f7c055ba7792021-12-02T17:31:42ZSUMO targets the APC/C to regulate transition from metaphase to anaphase10.1038/s41467-018-03486-42041-1723https://doaj.org/article/5797f95b8c1741f1b90f2f7c055ba7792018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03486-4https://doaj.org/toc/2041-1723Signal transduction by small ubiquitin-like modifier (SUMO) is important for cell cycle progression. Here the authors show that SUMOylation regulates the APC/C complex, a master orchestrator of metaphase to anaphase transition, with consequences for mitotic progression.Karolin EiflerSabine A. G. CuijpersEdwin WillemsteinJonne A. RaaijmakersDris El AtmiouiHuib OvaaRené H. MedemaAlfred C. O. VertegaalNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karolin Eifler Sabine A. G. Cuijpers Edwin Willemstein Jonne A. Raaijmakers Dris El Atmioui Huib Ovaa René H. Medema Alfred C. O. Vertegaal SUMO targets the APC/C to regulate transition from metaphase to anaphase
description	Signal transduction by small ubiquitin-like modifier (SUMO) is important for cell cycle progression. Here the authors show that SUMOylation regulates the APC/C complex, a master orchestrator of metaphase to anaphase transition, with consequences for mitotic progression.
format	article
author	Karolin Eifler Sabine A. G. Cuijpers Edwin Willemstein Jonne A. Raaijmakers Dris El Atmioui Huib Ovaa René H. Medema Alfred C. O. Vertegaal
author_facet	Karolin Eifler Sabine A. G. Cuijpers Edwin Willemstein Jonne A. Raaijmakers Dris El Atmioui Huib Ovaa René H. Medema Alfred C. O. Vertegaal
author_sort	Karolin Eifler
title	SUMO targets the APC/C to regulate transition from metaphase to anaphase
title_short	SUMO targets the APC/C to regulate transition from metaphase to anaphase
title_full	SUMO targets the APC/C to regulate transition from metaphase to anaphase
title_fullStr	SUMO targets the APC/C to regulate transition from metaphase to anaphase
title_full_unstemmed	SUMO targets the APC/C to regulate transition from metaphase to anaphase
title_sort	sumo targets the apc/c to regulate transition from metaphase to anaphase
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/5797f95b8c1741f1b90f2f7c055ba779
work_keys_str_mv	AT karolineifler sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT sabineagcuijpers sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT edwinwillemstein sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT jonnearaaijmakers sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT driselatmioui sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT huibovaa sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT renehmedema sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase AT alfredcovertegaal sumotargetstheapcctoregulatetransitionfrommetaphasetoanaphase
_version_	1718380492383846400

SUMO targets the APC/C to regulate transition from metaphase to anaphase

Ejemplares similares