SUMO targets the APC/C to regulate transition from metaphase to anaphase

SUMO targets the APC/C to regulate transition from metaphase to anaphase

Signal transduction by small ubiquitin-like modifier (SUMO) is important for cell cycle progression. Here the authors show that SUMOylation regulates the APC/C complex, a master orchestrator of metaphase to anaphase transition, with consequences for mitotic progression.

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Detalles Bibliográficos
Autores principales: Karolin Eifler, Sabine A. G. Cuijpers, Edwin Willemstein, Jonne A. Raaijmakers, Dris El Atmioui, Huib Ovaa, René H. Medema, Alfred C. O. Vertegaal
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/5797f95b8c1741f1b90f2f7c055ba779
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