Substrate specificity of the TRAMP nuclear surveillance complexes

During nuclear surveillance in yeast and human cells, the RNA exosome functions together with the TRAMP complexes. Here, the authors defined the protein composition of the TRAMP complexes and identified specific RNA binding sites for the different TRAMP components.

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Autores principales: Clémentine Delan-Forino, Christos Spanos, Juri Rappsilber, David Tollervey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/57a052a2d8ae4660914d242bac488c90
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spelling oai:doaj.org-article:57a052a2d8ae4660914d242bac488c902021-12-02T17:39:44ZSubstrate specificity of the TRAMP nuclear surveillance complexes10.1038/s41467-020-16965-42041-1723https://doaj.org/article/57a052a2d8ae4660914d242bac488c902020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16965-4https://doaj.org/toc/2041-1723During nuclear surveillance in yeast and human cells, the RNA exosome functions together with the TRAMP complexes. Here, the authors defined the protein composition of the TRAMP complexes and identified specific RNA binding sites for the different TRAMP components.Clémentine Delan-ForinoChristos SpanosJuri RappsilberDavid TollerveyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Clémentine Delan-Forino
Christos Spanos
Juri Rappsilber
David Tollervey
Substrate specificity of the TRAMP nuclear surveillance complexes
description During nuclear surveillance in yeast and human cells, the RNA exosome functions together with the TRAMP complexes. Here, the authors defined the protein composition of the TRAMP complexes and identified specific RNA binding sites for the different TRAMP components.
format article
author Clémentine Delan-Forino
Christos Spanos
Juri Rappsilber
David Tollervey
author_facet Clémentine Delan-Forino
Christos Spanos
Juri Rappsilber
David Tollervey
author_sort Clémentine Delan-Forino
title Substrate specificity of the TRAMP nuclear surveillance complexes
title_short Substrate specificity of the TRAMP nuclear surveillance complexes
title_full Substrate specificity of the TRAMP nuclear surveillance complexes
title_fullStr Substrate specificity of the TRAMP nuclear surveillance complexes
title_full_unstemmed Substrate specificity of the TRAMP nuclear surveillance complexes
title_sort substrate specificity of the tramp nuclear surveillance complexes
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/57a052a2d8ae4660914d242bac488c90
work_keys_str_mv AT clementinedelanforino substratespecificityofthetrampnuclearsurveillancecomplexes
AT christosspanos substratespecificityofthetrampnuclearsurveillancecomplexes
AT jurirappsilber substratespecificityofthetrampnuclearsurveillancecomplexes
AT davidtollervey substratespecificityofthetrampnuclearsurveillancecomplexes
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