Clinical Features of Segmental Infantile Hemangioma: A Prospective Study

Tong Qiu,1 Kaiying Yang,1 Shiyi Dai,1 Siyuan Chen,2 Yi Ji1 1Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, People’s Republic of China; 2Pediatric Intensive Care Unit, Department of Critical Care Medicine, West China Hospita...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Qiu T, Yang K, Dai S, Chen S, Ji Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	segmental infantile hemangioma clinical features complications treatment ulceration Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/57a4b454838545b28c96f7ebe610fce1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:57a4b454838545b28c96f7ebe610fce1
record_format	dspace
spelling	oai:doaj.org-article:57a4b454838545b28c96f7ebe610fce12021-12-02T13:53:34ZClinical Features of Segmental Infantile Hemangioma: A Prospective Study1178-203Xhttps://doaj.org/article/57a4b454838545b28c96f7ebe610fce12021-01-01T00:00:00Zhttps://www.dovepress.com/clinical-features-of-segmental-infantile-hemangioma-a-prospective-stud-peer-reviewed-article-TCRMhttps://doaj.org/toc/1178-203XTong Qiu,1 Kaiying Yang,1 Shiyi Dai,1 Siyuan Chen,2 Yi Ji1 1Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, People’s Republic of China; 2Pediatric Intensive Care Unit, Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu 610041, People’s Republic of ChinaCorrespondence: Yi JiDivision of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, #37# Guo-Xue-Xiang, Chengdu 610041, People’s Republic of ChinaFax +86 28 85423453Email jijiyuanyuan@163.comBackground: Infantile hemangioma (IH) is the most common benign tumor in children. However, few studies have reported the clinical features of segmental IH. We aimed to determine the clinical characteristics of segmental IH and to identify features that may aid clinicians in managing segmental IH.Methods: In the cross-sectional prospective study approved by the Ethics Committee of the hospital, children diagnosed with IH were recruited, and information including patient demographics, IH morphology and anatomical location, complications and treatments were recorded and analyzed.Results: In total, 153 patients with segmental IH and 1375 patients with nonsegmental IH were enrolled in this study. The average age on the day of the first visit in patients with segmental IH was 3.63± 3.23 months. In 69 patients (45.10%), segmental IH was diagnosed at birth. Most segmental IHs (49.67%) occurred in the limbs, while only 22.04% of nonsegmental IHs occurred in the extremities (P< 0.001). Thirteen patients (8.50%) with segmental IH had ulceration. Compared with patients with nonsegmental IHs, patients with segmental IHs were more likely to be treated with oral drugs (P< 0.001).Conclusion: Segmental IHs mainly occur in the extremities and are frequently diagnosed at birth. Segmental IHs are usually accompanied by ulceration, which are more commonly seen in the neck and perineal/perianal/genital areas than nonsegmental IHs. Oral propranolol is prescribed more often in patients with segmental IH than in those with nonsegmental IH.Keywords: segmental infantile hemangioma, clinical features, complications, treatment, ulcerationQiu TYang KDai SChen SJi YDove Medical Pressarticlesegmental infantile hemangiomaclinical featurescomplicationstreatmentulcerationTherapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 119-125 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	segmental infantile hemangioma clinical features complications treatment ulceration Therapeutics. Pharmacology RM1-950
spellingShingle	segmental infantile hemangioma clinical features complications treatment ulceration Therapeutics. Pharmacology RM1-950 Qiu T Yang K Dai S Chen S Ji Y Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
description	Tong Qiu,1 Kaiying Yang,1 Shiyi Dai,1 Siyuan Chen,2 Yi Ji1 1Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, People’s Republic of China; 2Pediatric Intensive Care Unit, Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu 610041, People’s Republic of ChinaCorrespondence: Yi JiDivision of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, #37# Guo-Xue-Xiang, Chengdu 610041, People’s Republic of ChinaFax +86 28 85423453Email jijiyuanyuan@163.comBackground: Infantile hemangioma (IH) is the most common benign tumor in children. However, few studies have reported the clinical features of segmental IH. We aimed to determine the clinical characteristics of segmental IH and to identify features that may aid clinicians in managing segmental IH.Methods: In the cross-sectional prospective study approved by the Ethics Committee of the hospital, children diagnosed with IH were recruited, and information including patient demographics, IH morphology and anatomical location, complications and treatments were recorded and analyzed.Results: In total, 153 patients with segmental IH and 1375 patients with nonsegmental IH were enrolled in this study. The average age on the day of the first visit in patients with segmental IH was 3.63± 3.23 months. In 69 patients (45.10%), segmental IH was diagnosed at birth. Most segmental IHs (49.67%) occurred in the limbs, while only 22.04% of nonsegmental IHs occurred in the extremities (P< 0.001). Thirteen patients (8.50%) with segmental IH had ulceration. Compared with patients with nonsegmental IHs, patients with segmental IHs were more likely to be treated with oral drugs (P< 0.001).Conclusion: Segmental IHs mainly occur in the extremities and are frequently diagnosed at birth. Segmental IHs are usually accompanied by ulceration, which are more commonly seen in the neck and perineal/perianal/genital areas than nonsegmental IHs. Oral propranolol is prescribed more often in patients with segmental IH than in those with nonsegmental IH.Keywords: segmental infantile hemangioma, clinical features, complications, treatment, ulceration
format	article
author	Qiu T Yang K Dai S Chen S Ji Y
author_facet	Qiu T Yang K Dai S Chen S Ji Y
author_sort	Qiu T
title	Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
title_short	Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
title_full	Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
title_fullStr	Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
title_full_unstemmed	Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
title_sort	clinical features of segmental infantile hemangioma: a prospective study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/57a4b454838545b28c96f7ebe610fce1
work_keys_str_mv	AT qiut clinicalfeaturesofsegmentalinfantilehemangiomaaprospectivestudy AT yangk clinicalfeaturesofsegmentalinfantilehemangiomaaprospectivestudy AT dais clinicalfeaturesofsegmentalinfantilehemangiomaaprospectivestudy AT chens clinicalfeaturesofsegmentalinfantilehemangiomaaprospectivestudy AT jiy clinicalfeaturesofsegmentalinfantilehemangiomaaprospectivestudy
_version_	1718392379446132736

Clinical Features of Segmental Infantile Hemangioma: A Prospective Study

Ejemplares similares