Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins

Abstract 14-3-3s represent a family of highly conserved 30 kDa acidic proteins. 14-3-3s recognize and bind specific phospho-sequences on client partners and operate as molecular hubs to regulate their activity, localization, folding, degradation, and protein–protein interactions. 14-3-3s are also as...

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Autores principales: E. Giusto, T. A. Yacoubian, E. Greggio, L. Civiero
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/57a55e33f86545c39431beb496763fde
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