Ribosomal Elongation Factor 4 Promotes Cell Death Associated with Lethal Stress
ABSTRACT Ribosomal elongation factor 4 (EF4) is highly conserved among bacteria, mitochondria, and chloroplasts. However, the EF4-encoding gene, lepA, is nonessential and its deficiency shows no growth or fitness defect. In purified systems, EF4 back-translocates stalled, posttranslational ribosomes...
Guardado en:
Autores principales: | Liping Li, Yuzhi Hong, Gan Luan, Michael Mosel, Muhammad Malik, Karl Drlica, Xilin Zhao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/57a842d42f714ce1b1a09aafe4542e8b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Elongation Factor P Interactions with the Ribosome Are Independent of Pausing
por: Rodney Tollerson, et al.
Publicado: (2017) -
Genome-scale analysis of translation elongation with a ribosome flow model.
por: Shlomi Reuveni, et al.
Publicado: (2011) -
Tuning of the Lethal Response to Multiple Stressors with a Single-Site Mutation during Clinical Infection by <italic toggle="yes">Staphylococcus aureus</italic>
por: Krishan Kumar, et al.
Publicado: (2017) -
Determinants of translation elongation speed and ribosomal profiling biases in mouse embryonic stem cells.
por: Alexandra Dana, et al.
Publicado: (2012) -
Promoter-proximal elongation regulates transcription in archaea
por: Fabian Blombach, et al.
Publicado: (2021)