Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice.

Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice.

Recent evidence indicates that toll-like receptor (TLR) 2 and 4 are involved in the pathogenesis of dilated cardiomyopathy (DCM), but the exact mechanisms of their actions have not been elucidated. We explored the therapeutic potential of blocking TLRs in mice with established cardiomyopathy. Cardio...

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Autores principales: Yonggang Ma, Xiaowei Zhang, Huayan Bao, Su Mi, Wenfeng Cai, Huimin Yan, Qingqing Wang, Ziyan Wang, Jun Yan, Guo-Chang Fan, Merry L Lindsey, Zhuowei Hu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/57bd32d6ad9c48acab6e47ee9176c79a
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