Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

Riboswitches are non-coding RNA elements that detect metabolites and control expression by regulating mRNA levels or translation. Here, the authors provide evidence that theE. coli thiC riboswitch has a pause site in the translation initiation region that acts as a checkpoint for thiCexpression.

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Autores principales:	Adrien Chauvier, Frédéric Picard-Jean, Jean-Christophe Berger-Dancause, Laurène Bastet, Mohammad Reza Naghdi, Audrey Dubé, Pierre Turcotte, Jonathan Perreault, Daniel A. Lafontaine
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/57c5865f15864c03ba74e3b730ffa5e6
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spelling	oai:doaj.org-article:57c5865f15864c03ba74e3b730ffa5e62021-12-02T15:38:33ZTranscriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation10.1038/ncomms138922041-1723https://doaj.org/article/57c5865f15864c03ba74e3b730ffa5e62017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13892https://doaj.org/toc/2041-1723Riboswitches are non-coding RNA elements that detect metabolites and control expression by regulating mRNA levels or translation. Here, the authors provide evidence that theE. coli thiC riboswitch has a pause site in the translation initiation region that acts as a checkpoint for thiCexpression.Adrien ChauvierFrédéric Picard-JeanJean-Christophe Berger-DancauseLaurène BastetMohammad Reza NaghdiAudrey DubéPierre TurcotteJonathan PerreaultDaniel A. LafontaineNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Adrien Chauvier Frédéric Picard-Jean Jean-Christophe Berger-Dancause Laurène Bastet Mohammad Reza Naghdi Audrey Dubé Pierre Turcotte Jonathan Perreault Daniel A. Lafontaine Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
description	Riboswitches are non-coding RNA elements that detect metabolites and control expression by regulating mRNA levels or translation. Here, the authors provide evidence that theE. coli thiC riboswitch has a pause site in the translation initiation region that acts as a checkpoint for thiCexpression.
format	article
author	Adrien Chauvier Frédéric Picard-Jean Jean-Christophe Berger-Dancause Laurène Bastet Mohammad Reza Naghdi Audrey Dubé Pierre Turcotte Jonathan Perreault Daniel A. Lafontaine
author_facet	Adrien Chauvier Frédéric Picard-Jean Jean-Christophe Berger-Dancause Laurène Bastet Mohammad Reza Naghdi Audrey Dubé Pierre Turcotte Jonathan Perreault Daniel A. Lafontaine
author_sort	Adrien Chauvier
title	Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
title_short	Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
title_full	Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
title_fullStr	Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
title_full_unstemmed	Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
title_sort	transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/57c5865f15864c03ba74e3b730ffa5e6
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Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

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